SCHEMBL61019

SCHEMBL61019

[CH2]CC(F)(F)C(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492136 0.82 KDM4E (0.33)
SCHEMBL7102626 0.80 TSHR (0.33)
SCHEMBL717488 0.78 TSHR (0.36)
SCHEMBL15402357 0.78
SCHEMBL476544 0.78 TSHR (0.36)
SCHEMBL476596 0.78 TSHR (0.36)
SCHEMBL15403272 0.78
SCHEMBL476526 0.78 TSHR (0.36)
SCHEMBL15403706 0.77
SCHEMBL2488959 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11007968-B2 Fibrous support comprising a silicone coating ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2021-05-18 US claimed
EP-1401964-B1 SILICONE COMPOSITION CROSSLINKABLE INTO ELASTOMER BY HYDROSILYLATION, IN THE PRESENCE OF CARBENE-BASED METAL CATALYSTS, AND CATALYSTS BLUESTAR SILICONES FRANCE (FR) 2009-04-15 EP claimed
US-7202320-B2 Silicone composition crosslinkable into elastomer by hydrosilylation, in the presence of carbene-based metal catalysts, and catalysts RHODIA CHIMIE (FR) 2007-04-10 US claimed
US-20040236054-A1 Silicone composition crosslinkable into elastomer by hydrosilylation, in the presence of carbene-based metal catalysts, and catalysts BLUESTAR SILICONES FRANCE SAS (FR) 2004-11-25 US claimed
CN-111868196-B Polyorganosiloxane hot melt adhesive compositions containing polyolefin-polydiorganosiloxane copolymers and methods of making and using the same 美国陶氏有机硅公司 2022-08-30 CN disclosed
CN-111918904-B Polyolefin-polydiorganosiloxane block copolymers and methods of synthesizing the same 美国陶氏有机硅公司 2022-08-19 CN disclosed
CN-111886314-B Hot melt adhesive compositions containing polyolefin-polydiorganosiloxane block copolymers and methods of making and using the same 美国陶氏有机硅公司 2022-06-17 CN disclosed
CN-113165333-A Multilayer films and laminates containing slip agents 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-11007968-B2 Fibrous support comprising a silicone coating ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2021-05-18 US disclosed
CN-111918904-A Polyolefin-polydiorganosiloxane block copolymers and methods of synthesizing the same 美国陶氏有机硅公司 2020-11-10 CN disclosed
CN-111886314-A Hot melt adhesive compositions containing polyolefin-polydiorganosiloxane block copolymers and methods of making and using the same 美国陶氏有机硅公司 2020-11-03 CN disclosed
CN-111868196-A Polyorganosiloxane hot melt adhesive compositions containing polyolefin-polydiorganosiloxane copolymers and methods of making and using the same 美国陶氏有机硅公司 2020-10-30 CN disclosed
US-20060019106-A1 Anti-soil silicone varnish compositions and support substrates treated therewith RHODIA CHIMIE (FR) 2006-01-26 US disclosed
WO-2005063694-A1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 WO disclosed
US-6902816-B1 Silicone composition used in the production of antifriction varnishes, method for the application of said varnishes to a support and support thus treated RHODIA CHIMIE (FR) 2005-06-07 US disclosed
US-20050037210-A1 Silicone composition used in the production of antifriction varnishes, method for the application of said varnishes to a support and support thus treated BERTRY JEAN-LOUIS (FR) 2005-02-17 US disclosed
US-20040236054-A1 Silicone composition crosslinkable into elastomer by hydrosilylation, in the presence of carbene-based metal catalysts, and catalysts BLUESTAR SILICONES FRANCE SAS (FR) 2004-11-25 US disclosed
US-6314668-B1 Household appliance and cassette with disincrustant means, and disincrustant method in a household appliance SEB S.A. (FR) 2001-11-13 US disclosed
US-6284829-B1 FILLER COMPRISING AT LEAST TWO GROUPS OF PARTICLES OF VERY DIFFERENT MEAN DIAMETERS RHODIA CHIMIE (FR) 2001-09-04 US disclosed
US-5998536-A BLEND OF POLYSILOXANE AND PROTECTIVE COLLOID RHONE-POULENC CHIMIE (FR) 1999-12-07 US disclosed