SCHEMBL2492136

SCHEMBL2492136

[CH2]CC(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102626 0.92 TSHR (0.33) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL476526 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL476544 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL717488 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL476596 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL61019 0.82
SCHEMBL15404541 0.79
SCHEMBL15404998 0.79
SCHEMBL3034719 0.79 KDM4E (0.31) KDM4ETSHRTDP1
SCHEMBL15402521 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240231231-A1 METHOD FOR FORMING RESIST UNDERLAYER FILM, METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE, COMPOSITION, AND RESIST UNDERLAYER FILM JSR CORPORATION (JP) 2024-07-11 US disclosed
US-20240184203-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM, METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE, AND METHOD FOR FORMING RESIST UNDERLAYER FILM JSR CORPORATION (JP) 2024-06-06 US disclosed
CN-117642698-A Composition for forming resist underlayer film, method for producing semiconductor substrate, and method for forming resist underlayer film JSR株式会社 2024-03-01 CN disclosed
US-20230041656-A1 COMPOSITION, METHOD OF FORMING RESIST UNDERLAYER FILM, AND METHOD OF FORMING RESIST PATTERN JSR CORPORATION (JP) 2023-02-09 US disclosed
WO-2023008149-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM, METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE, AND METHOD FOR FORMING RESIST UNDERLAYER FILM JSR株式会社 2023-02-02 WO disclosed
EP-1589367-B1 PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC MENICON CO LTD (JP) 2019-03-13 EP disclosed
US-8901170-B2 Malononitrile compounds BASF SE (DE) 2014-12-02 US disclosed
CN-103666006-A Surfactant, coating composite and resist composition DAINIPPON INK & CHEMICALS 2014-03-26 CN disclosed
CN-101506150-B Malononitrile compounds BASF SE 2013-08-28 CN disclosed
EP-1697311-B1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2011-10-26 EP disclosed
WO-2007147888-A1 MALONONITRILE COMPOUNDS BASF SE (DE) 2007-12-27 WO disclosed
US-20070112068-A1 Nitrile compound and its use in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-17 US disclosed
EP-1566684-B1 LENS FOR EYE AND METHOD FOR MARKING THEREOF MENICON CO LTD (JP) 2007-03-14 EP disclosed
CN-1898200-A Nitrile compound and its pest control use SUMITOMO CHEMICAL CO (JP) 2007-01-17 CN disclosed
EP-1697311-A1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2006-09-06 EP disclosed
US-7044598-B2 Lens for eye and method for marking thereof MENICON CO., LTD.. (JP) 2006-05-16 US disclosed
EP-1589367-A1 PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC MENICON CO., LTD. (JP) 2005-10-26 EP disclosed
US-20050206843-A1 Lens for eye and method for marking thereof MENICON CO., LTD. (JP) 2005-09-22 US disclosed
EP-1566684-A1 LENS FOR EYE AND METHOD FOR MARKING THEREOF MENICON CO., LTD. (JP) 2005-08-24 EP disclosed
WO-2005063694-A1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070112068-A1 Nitrile compound and its use in pest control C5, C9, C1S KDM4E 863/4885TSHR 1172/4885TDP1 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.