Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476596 | 0.97 | TSHR (0.36) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL476544 | 0.97 | TSHR (0.36) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL476526 | 0.97 | TSHR (0.36) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL717488 | 0.97 | TSHR (0.36) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL2492136 | 0.92 | KDM4E (0.33) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL61019 | 0.80 | — | — | |
| SCHEMBL12971185 | 0.80 | — | — | |
| SCHEMBL18787351 | 0.78 | — | — | |
| SCHEMBL3477264 | 0.78 | — | — | |
| SCHEMBL9513952 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410612-B1 | ACRYLIC POLYMER BLEND | KURARAY CO., LTD. (JP) | 2002-06-25 | — | — | US | claimed |
| EP-2684870-A1 | METHOD FOR PREPARING THIOCARBOXYLIC ACID S-(FLUOROALKYL) ESTER | Sumitomo Chemical Company Limited (JP) | 2014-01-15 | — | — | EP | disclosed |
| EP-1033125-B1 | Relining material for dentures | KURARAY CO (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6410612-B1 | ACRYLIC POLYMER BLEND | KURARAY CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1033125-A1 | Relining material for dentures | KURARAY CO., LTD. (JP) | 2000-09-06 | — | — | EP | disclosed |