Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476544 | 1.00 | TSHR (0.36) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL476596 | 1.00 | TSHR (0.36) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL717488 | 1.00 | TSHR (0.36) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7102626 | 0.97 | TSHR (0.33) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL2492136 | 0.90 | KDM4E (0.33) | TSHRCYP1A2CYP2C19KDM4ETDP1 | |
| SCHEMBL18787351 | 0.81 | — | — | |
| SCHEMBL3477264 | 0.81 | — | — | |
| SCHEMBL9513952 | 0.81 | — | — | |
| SCHEMBL12971266 | 0.81 | — | — | |
| SCHEMBL61019 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317297-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | STRUCTO PTE LTD (SG) | 2021-10-14 | — | — | US | disclosed |
| EP-3820398-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | Structo Pte. Ltd. (SG) | 2021-05-19 | — | — | EP | disclosed |
| EP-1589367-B1 | PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC | MENICON CO LTD (JP) | 2019-03-13 | — | — | EP | disclosed |
| US-20180356561-A1 | GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER | JSR CORPORATION (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-2453292-B1 | SOFT HYBRID CONTACT LENS, METHOD FOR PRODUCING SAME, AND HYDRATION METHOD | MENICON CO LTD (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2103636-B1 | FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION | JNC CORP (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-9017716-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| EP-2180366-B1 | SILICONE-CONTAINING OCULAR LENS MATERIAL WITH HIGH SAFETY AND PREPARING METHOD THEREOF | MENICON CO LTD (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-8445613-B2 | Polymer and surface-treating agent containing the polymer | JNC CORPORATION (JP) | 2013-05-21 | — | — | US | disclosed |
| EP-0657751-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |
| EP-0379146-B1 | Soft ocular lens material | MENICON CO LTD (JP) | 1995-05-17 | — | — | EP | disclosed |
| US-5416132-A | Acrylamide modified acrylate modified polysiloxanes | MENICON CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0381005-B1 | Ocular lens material | MENICON CO LTD (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5346946-A | Polysiloxane macromonomer | MENICON CO., LTD (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0584826-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584764-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041511-A | Vinyl benzene acrylate or methacrylate crosslinking agent | MENICON CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| US-4954586-A | COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE | MENICON CO., LTD (JP) | 1990-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | CRYZ, CRYAA, VIL1 | TSHR 4720/4885USP2 3095/4885MAPT 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.