Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708841 | 0.90 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708871 | 0.90 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708802 | 0.90 | NPC1 (0.61) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6100830 | 0.88 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6102970 | 0.86 | NPC1 (0.53) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708725 | 0.85 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708842 | 0.82 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708803 | 0.78 | NPC1 (0.53) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708786 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5708874 | 0.76 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040919-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2006-02-23 | — | — | US | disclosed |
| US-20050165004-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165004-A1 | Bronchorelaxing compounds | GPR6, CHRM3, NR1H3 | MEN1 1409/4885KMT2A 3030/4885SMN1; SMN2 2872/4885 |
| US-20060040919-A1 | Bronchorelaxing compounds | CHRM3, GPR3, CHRM2 | MEN1 2210/4885KMT2A 3875/4885SMN1; SMN2 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.