Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102785 | 1.00 | SFRP1 (0.56) | SFRP1TP53CA1CA2GRIA4 | |
| SCHEMBL4616930 | 0.93 | SFRP1 (0.64) | SFRP1TP53GRIA4GBA1LMNA | |
| SCHEMBL6102783 | 0.93 | SFRP1 (0.64) | SFRP1TP53GRIA4GBA1LMNA | |
| SCHEMBL6101141 | 0.91 | SFRP1 (0.58) | SFRP1TP53GRIA4GBA1LMNA | |
| SCHEMBL6100041 | 0.91 | SFRP1 (0.58) | SFRP1TP53GRIA4GBA1LMNA | |
| SCHEMBL4618430 | 0.89 | SFRP1 (0.54) | SFRP1TP53CA1CA2GBA1 | |
| SCHEMBL6103324 | 0.88 | ALDH1A1 (0.57) | SFRP1TP53CA1CA2LMNA | |
| SCHEMBL6102984 | 0.88 | ALDH1A1 (0.57) | SFRP1TP53CA1CA2LMNA | |
| SCHEMBL6102667 | 0.87 | CA1 (0.47) | SFRP1TP53CA1CA2GRIA4 | |
| SCHEMBL6102023 | 0.87 | CA1 (0.47) | SFRP1TP53CA1CA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | claimed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | SFRP1, SOS1, FZD7 | SFRP1 1/4885TP53 4653/4885CA1 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.