SCHEMBL610429

SCHEMBL610429

CCN(CC)Sc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
HPGD P15428 4/20 0.57
RAB9A P51151 4/20 0.49
NPC1 O15118 1/20 0.49
SRD5A2 P31213 1/20 0.47
ELANE P08246 2/20 0.46
LMNA P02545 2/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
MAPT P10636 1/20 0.42
MAPK13 O15264 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611208 0.93 HPGD (0.46) ALDH1A1HPGDRAB9ANPC1SRD5A2
SCHEMBL609847 0.85 L3MBTL1 (0.52) ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1
SCHEMBL610063 0.80 HPGD (0.55) ALDH1A1HPGDRAB9ALMNAMEN1
SCHEMBL611875 0.80 HPGD (0.58) ALDH1A1HPGDRAB9ANPC1SRD5A2
SCHEMBL11356807 0.77 ALDH1A1 (0.54) ALDH1A1HPGDRAB9ANPC1SRD5A2
SCHEMBL3448940 0.76 THRA (0.41) ALDH1A1HPGDLMNAMAPT
Benzophenone SCHEMBL8962994 0.75 ALDH1A1 (0.66) ALDH1A1HPGDRAB9ANPC1SRD5A2
Benzophenone SCHEMBL5483630 0.75 ALDH1A1 (0.66) ALDH1A1HPGDRAB9ANPC1SRD5A2
Benzophenone SCHEMBL27611611 0.75 ALDH1A1 (0.66) ALDH1A1HPGDRAB9ANPC1SRD5A2
Benzophenone SCHEMBL8089683 0.74 ALDH1A1 (0.78) ALDH1A1HPGDRAB9ANPC1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed