Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740320 | 0.91 | POLB (0.35) | POLBBRD4OPRM1SMN1; SMN2ATM | |
| SCHEMBL15624086 | 0.82 | OPRM1 (0.38) | POLBBRD4OPRM1SMN1; SMN2OPRD1 | |
| SCHEMBL23065403 | 0.82 | OPRM1 (0.38) | POLBOPRM1SMN1; SMN2ATMOPRD1 | |
| SCHEMBL16107365 | 0.80 | SMN1; SMN2 (0.39) | POLBBRD4OPRM1SMN1; SMN2OPRD1 | |
| SCHEMBL12496432 | 0.80 | POLB (0.34) | POLBBRD4OPRM1SMN1; SMN2ATM | |
| SCHEMBL10938727 | 0.80 | SMN1; SMN2 (0.39) | POLBOPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL10118790 | 0.79 | POLB (0.36) | POLBBRD4OPRM1SMN1; SMN2ATM | |
| SCHEMBL18309370 | 0.78 | ATM (0.35) | POLBBRD4OPRM1SMN1; SMN2ATM | |
| SCHEMBL24425852 | 0.78 | ATM (0.35) | POLBBRD4OPRM1SMN1; SMN2ATM | |
| SCHEMBL24425886 | 0.77 | BRD4 (0.33) | POLBBRD4OPRM1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250042854-A1 | IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF | ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES (FR) | 2025-02-06 | — | — | US | disclosed |
| EP-4433451-A1 | IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF | Ecole Nationale Supérieure de Chimie de Rennes (FR) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023088919-A1 | IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF | ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) | 2023-05-25 | — | — | WO | disclosed |
| US-11517832-B2 | System and method for removing transition metals from solution | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-12-06 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3129347-B1 | REACTIONS IN THE PRESENCE OF RUTHENIUM COMPLEXES | CALIFORNIA INST OF TECHN (US) | 2021-10-06 | — | — | EP | disclosed |
| US-7241898-B2 | Metathesis catalysts | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| WO-2007075427-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | MATERIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| EP-1743899-A1 | Metal complexes for use in metathesis, atom transfer radical reactions, addition polymerisation and vinylation reactions, methods and intermediates for making them | Universiteit Gent (BE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1394190-B1 | Metathesis catalysts | SALTIGO GMBH (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1468004-B1 | METAL COMPLEXES FOR USE IN METATHESIS | UNIV GENT (BE) | 2006-12-20 | — | — | EP | disclosed |
| US-20050049417-A1 | Metathesis catalysts | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-03-03 | — | — | US | disclosed |
| US-4670041-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
| US-4567283-A | EPOXYCYCLOHEXANOLS | SHELL OIL COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| US-4554366-A | HERBICIDES, PLANT GROWTH REGULATORS | SHELL OIL COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4542244-A | Oxabicycloalkane herbicides | SHELL OIL COMPANY (US) | 1985-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | POLB 316/4885BRD4 2536/4885OPRM1 292/4885 |
| US-20050049417-A1 | Metathesis catalysts | CYP1B1, MSMO1, CYP1A1 | POLB 679/4885BRD4 3447/4885OPRM1 1438/4885 |
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | POLB 316/4885BRD4 2536/4885OPRM1 292/4885 |
| US-20250042854-A1 | IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF | SQLE, SYMPK, FDFT1 | POLB 1763/4885BRD4 187/4885OPRM1 1157/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | POLB 316/4885BRD4 2536/4885OPRM1 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.