Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109273 | 0.89 | DPP4 (0.50) | DPP4PLA2G2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6108734 | 0.88 | AVPR1B (0.38) | AVPR1BSMN1; SMN2 | |
| SCHEMBL6109987 | 0.88 | GSK3B (0.36) | DPP4AVPR1BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6109710 | 0.87 | MAPK8 (0.42) | AVPR1BKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6108293 | 0.86 | PGR (0.36) | AVPR1BKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6109022 | 0.85 | GSK3B (0.33) | PLA2G2AAVPR1BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6109701 | 0.84 | ITGB1 (0.34) | AVPR1BKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6109441 | 0.84 | PARP15 (0.35) | AVPR1B | |
| SCHEMBL6109595 | 0.82 | AR (0.38) | DPP4KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5235599 | 0.81 | DPP4 (0.43) | DPP4PLA2G2AAVPR1BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |