Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107796 | 0.96 | PARP10 (0.38) | PARP15PARP10AVPR1BEDNRBEDNRA | |
| SCHEMBL6107384 | 0.90 | HTT (0.36) | PPARGPPARAITGB3ITGA2B | |
| SCHEMBL6109866 | 0.88 | PGR (0.39) | AVPR1B | |
| SCHEMBL6106201 | 0.88 | SMN1; SMN2 (0.36) | AVPR1BPPARGPPARAITGB3ITGA2B | |
| SCHEMBL6109860 | 0.88 | L3MBTL1 (0.34) | MTNR1APPARGPPARDPPARAMAOB | |
| SCHEMBL6107351 | 0.87 | CNR1 (0.36) | AVPR1BPPARGPPARA | |
| SCHEMBL6110636 | 0.87 | MAPT (0.34) | AVPR1BEDNRBEDNRAPPARGPPARD | |
| SCHEMBL6108410 | 0.87 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL6108162 | 0.87 | HTT (0.35) | PPARGPPARAMAOB | |
| SCHEMBL6109595 | 0.87 | AR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |