Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107384 | 0.91 | HTT (0.36) | ALDH1A1CNR1CNR2KDM4EHPGD | |
| SCHEMBL6109866 | 0.90 | PGR (0.39) | ALDH1A1DPP4KDM4EHPGDRAB9A | |
| SCHEMBL6106201 | 0.89 | SMN1; SMN2 (0.36) | ALDH1A1DPP4CNR1CNR2KDM4E | |
| SCHEMBL6107351 | 0.89 | CNR1 (0.36) | ALDH1A1CNR1CNR2KDM4EHPGD | |
| SCHEMBL6110636 | 0.89 | MAPT (0.34) | ALDH1A1DPP4PSEN1PSEN2APH1B | |
| SCHEMBL6108410 | 0.89 | PPARG (0.34) | ALDH1A1DPP4CNR1CNR2KDM4E | |
| SCHEMBL6108162 | 0.88 | HTT (0.35) | ALDH1A1CNR1CNR2KDM4ENPC1 | |
| SCHEMBL6108036 | 0.88 | CNR1 (0.39) | ALDH1A1DPP4CNR1CNR2KDM4E | |
| SCHEMBL6107972 | 0.88 | HTT (0.36) | ALDH1A1DPP4CNR1CNR2KDM4E | |
| SCHEMBL6108885 | 0.88 | RORA (0.36) | ALDH1A1DPP4CNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |