Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107972 | 0.98 | HTT (0.36) | SMN1; SMN2MAPK1PPARGPPARATSHR | |
| SCHEMBL6108036 | 0.96 | CNR1 (0.39) | SMN1; SMN2MAPK1PPARGPPARATSHR | |
| SCHEMBL6107172 | 0.94 | PGR (0.39) | TSHRHSD17B10PLA2G2AKDM4EALDH1A1 | |
| SCHEMBL6107384 | 0.94 | HTT (0.36) | SMN1; SMN2MAPK1PPARGPPARATSHR | |
| SCHEMBL6110359 | 0.93 | MEN1 (0.34) | SMN1; SMN2MAPK1PPARGPPARATSHR | |
| SCHEMBL6109262 | 0.92 | MMP2 (0.39) | SMN1; SMN2PPARGPPARAPLA2G2AALDH1A1 | |
| SCHEMBL6107351 | 0.92 | CNR1 (0.36) | SMN1; SMN2PPARGPPARATSHRHSD17B10 | |
| SCHEMBL6110589 | 0.92 | RORA (0.33) | SMN1; SMN2MAPK1PPARGPPARATSHR | |
| SCHEMBL6108005 | 0.91 | PTGDR2 (0.36) | SMN1; SMN2MAPK1TSHRHSD17B10CNR1 | |
| SCHEMBL6109866 | 0.91 | PGR (0.39) | TSHRHSD17B10DPP4PLA2G2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |