Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.94 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4472414 | 1.00 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL11066280 | 1.00 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL5157485 | 1.00 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL11068109 | 0.97 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL11068107 | 0.97 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL11062657 | 0.97 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL11062655 | 0.97 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ammonia Solution, Strong SCHEMBL11066264 | 0.97 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL597672 | 0.97 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL3409457 | 0.97 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 861 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569092-A | Small-particle-size spheroidal alumina product and preparation method thereof | 雅安百图高新材料股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119280450-A | Medical fabric dressing with long-acting disinfection and sterilization functions and preparation method thereof | 孙国明 | 2025-01-10 | — | — | CN | claimed |
| CN-114430057-B | Hydrogen production system, and hydrogen production method and power system using same | 南开大学 | 2024-12-24 | — | — | CN | claimed |
| CN-119100365-A | Sulfur-nitrogen double-doped porous hard carbon and preparation method and application thereof | 赣州立探新能源科技有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-118844836-A | Long-acting disinfection and sterilization wet (towel) paper | 孙国明 | 2024-10-29 | — | — | CN | claimed |
| CN-118844448-A | Preparation method of long-acting antibacterial liquid | 孙国明 | 2024-10-29 | — | — | CN | claimed |
| CN-118681068-A | Preparation method and application of mesoporous organosilicon nano gene transporter/hydroxyapatite composite coating | 中国人民解放军海军军医大学第二附属医院 | 2024-09-24 | — | — | CN | claimed |
| CN-117942305-A | Gemcitabine liposome with high encapsulation efficiency | 三峡大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117790729-A | Negative electrode composite material, preparation method and application thereof | 厦门海辰储能科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-115433376-A | Preparation method of long-acting disinfection and sterilization fabric or fiber | 孙国明 | 2022-12-06 | — | — | CN | claimed |
| WO-1998031667-A1 | AMINO-IMINOISOINDOLENINE BENZENE SULFONATE, AND PROCESS FOR THE PREPARATION OF NITRATE AND BENZENE SULFONATE SALTS OF AMINO-AMINOISOINDOLENINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-07-23 | — | — | WO | claimed |
| CN-1183791-A | Polyisocyanate composition having high emulsifiability and stability, and aqueous coating composition comprising said composition | ASAHI CHEMICAL IND (JP) | 1998-06-03 | — | — | CN | claimed |
| EP-0400657-B1 | Process for developing of ps plates requiring no dampening water | FUJI PHOTO FILM CO LTD (JP) | 1996-03-27 | — | — | EP | claimed |
| EP-0675117-A1 | Bromopropargyl quaternary ammonium compounds having antimicrobial activity | ROHM AND HAAS COMPANY (US) | 1995-10-04 | — | — | EP | claimed |
| US-5290665-A | Process for developing PS plate requiring no dampening water wherein the developer comprises, water, a solubilizer and an ethylene glycol mono(alkyl C6 -C8) ether derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| EP-0400657-A2 | Process for developing of ps plates requiring no dampening water | Fuji Photo Film Co., Ltd. (JP) | 1990-12-05 | — | — | EP | claimed |
| CN-1030769-A | The improvement of hexafluoropropylene (HFP)/tetrafluoroethylene (TFE) copolymerization process | SHANGHAI INST OF ORGANO FLUORO (CN) | 1989-02-01 | — | — | CN | claimed |
| WO-1979000977-A1 | METHOD FOR THE MANUFACTURE OF ADHESIVE PRODUCTS AND AN ADHESIVE PRODUCT MANUFACTURED ACCORDING TO THE METHOD | EDLER & CO FAERGIND AB (SE) | 1979-11-29 | — | — | WO | claimed |
| US-3948600-A | Selected ammonium sulfonate catalysts for an improved process utilizing mild curing conditions in durable press finishing of cellulose-containing fabrics | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-04-06 | — | — | US | claimed |
| US-3943134-A | FROM ACETONE AND AMMONIA, AMMONIUM HALIDE CATALYST | SANKYO COMPANY LIMITED (JA) | 1976-03-09 | — | — | US | claimed |