Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RORA | P35398 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | RORB | Q92753 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108885 | 0.96 | RORA (0.36) | MEN1KMT2ARORARORCRORB | |
| SCHEMBL6106201 | 0.93 | SMN1; SMN2 (0.36) | ALDH1A1ITGB1ITGA4MAPK1SMN1; SMN2 | |
| SCHEMBL6110589 | 0.92 | RORA (0.33) | MEN1KMT2ARORARORCRORB | |
| SCHEMBL6107172 | 0.91 | PGR (0.39) | RORARORCRORBPGRALDH1A1 | |
| SCHEMBL6108005 | 0.91 | PTGDR2 (0.36) | PTGER4MAPK1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL6107972 | 0.91 | HTT (0.36) | MEN1KMT2AALDH1A1ITGB1ITGA4 | |
| SCHEMBL6108036 | 0.91 | CNR1 (0.39) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6107738 | 0.89 | RORA (0.38) | RORARORCRORBPGRPPARG | |
| SCHEMBL6109288 | 0.88 | GAA (0.36) | ALDH1A1ITGB1ITGA4SMN1; SMN2TSHR | |
| SCHEMBL6107102 | 0.88 | RORA (0.35) | MEN1KMT2ARORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |