Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL721237 | 1.00 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL5505287 | 0.81 | SIGMAR1 (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL29215999 | 0.79 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL30533389 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL6054094 | 0.77 | HTR2A (0.35) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL6732035 | 0.76 | BRD4 (0.31) | HTR2AHTR6BRD4CCL2 | |
| Hydrochloric Acid SCHEMBL7947947 | 0.75 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL647140 | 0.75 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL218233 | 0.75 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL273051 | 0.74 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962899-B2 | Metalworking lubricant | IDEMITSU KOSAN CO., LTD. (JP) | 2015-02-24 | — | — | US | claimed |
| CN-104159929-A | Supported composite metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same | SK INNOVATION CO LTD | 2014-11-19 | — | — | CN | claimed |
| US-8557902-B2 | Functionalizable synthetic hydrocarbon fluids and integrated method for production thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-15 | — | — | US | claimed |
| EP-2609125-A2 | FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2013-07-03 | — | — | EP | claimed |
| US-20120053309-A1 | Functionalizable Synthetic Hydrocarbon Fluids and Integrated Method for Production Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-03-01 | — | — | US | claimed |
| WO-2012027139-A2 | FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-03-01 | — | — | WO | claimed |
| US-8063163-B2 | Cycloolefin copolymer | Polypastics Co., Ltd. (JP) | 2011-11-22 | — | — | US | claimed |
| EP-1645570-A2 | A process for co-polymerization of olefins | FINA Technology, Inc. (US) | 2006-04-12 | — | — | EP | claimed |
| US-6037296-A | USED FOR PRODUCTION OF HIGH DENSITY ETHYLENE POLYMERS AND COPOLYMERS | MOBIL OIL CORPORATION (US) | 2000-03-14 | — | — | US | claimed |
| EP-0874003-A1 | Process for co-polymerization of olefins | FINA TECHNOLOGY, INC. (US) | 1998-10-28 | — | — | EP | claimed |
| US-5789502-A | METALLOCENE CATALYST | FINA TECHNOLOGY, INC. (US) | 1998-08-04 | — | — | US | claimed |
| EP-2380918-B1 | PROCESS FOR PRODUCING ALPHA-OLEFIN POLYMER, ALPHA-OLEFIN POLYMER, AND LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2019-07-24 | — | — | EP | disclosed |
| CN-109963888-A | It is used to prepare the method for being suitable for bull or double end composition that chain shuttle moves | 陶氏环球技术有限责任公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-109952324-A | The sealing end bull or double end composition that are moved suitable for chain shuttle and preparation method | 陶氏环球技术有限责任公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109937217-A | The bull or double end composition that are moved suitable for chain shuttle and preparation method | 陶氏环球技术有限责任公司 | 2019-06-25 | — | — | CN | disclosed |
| EP-0707016-B1 | Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst | JAPAN POLYOLEFINS CO LTD (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0789624-A1 | CATALYST FOR BIOMODAL MOLECULAR WEIGHT DISTRIBUTION ETHYLENE POLYMERS AND COPOLYMERS | MOBIL OIL CORPORATION (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5614456-A | Catalyst for bimodal molecular weight distribution ethylene polymers and copolymers | MOBIL OIL CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1996014154-A1 | CATALYST FOR BIOMODAL MOLECULAR WEIGHT DISTRIBUTION ETHYLENE POLYMERS AND COPOLYMERS | MOBIL OIL CORPORATION (US) | 1996-05-17 | — | — | WO | disclosed |
| EP-0707016-A1 | Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst | JAPAN POLYOLEFINS CO., LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |