Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108951 | 0.88 | TP53 (0.38) | TSHRLMNAMAPK1NPSR1KDM4E | |
| SCHEMBL6109924 | 0.88 | DPP4 (0.32) | NPSR1ALDH1A1 | |
| SCHEMBL6109843 | 0.87 | DPP4 (0.35) | ALDH1A1 | |
| SCHEMBL6108264 | 0.86 | ALDH1A1 (0.38) | PLA2G2AMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL6110444 | 0.84 | THRB (0.34) | PLA2G2ANPSR1 | |
| SCHEMBL6106935 | 0.84 | PTGER4 (0.32) | NPSR1ALDH1A1 | |
| SCHEMBL6109704 | 0.84 | KDM4E (0.31) | TLR7GSK3BKDM4EALDH1A1 | |
| SCHEMBL6107057 | 0.84 | DPP4 (0.33) | KDM4E | |
| SCHEMBL5239221 | 0.83 | PDE4A (0.41) | TLR7MAPK8PLA2G2APDE4APDE4B | |
| SCHEMBL6107927 | 0.83 | CTSK (0.32) | LMNAKDM4EALDH1A1ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |