Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221256 | 0.82 | CA2 (0.60) | CA2CA1PPARACA12CA14 | |
| SCHEMBL7085537 | 0.81 | CA2 (0.63) | CA2CA1PPARACA12CA14 | |
| SCHEMBL7081057 | 0.81 | CA2 (0.63) | CA2CA1PPARACA12CA14 | |
| SCHEMBL4563383 | 0.79 | PPARA (0.86) | CA2CA1PPARACA12CA14 | |
| SCHEMBL9285865 | 0.77 | PPARA (0.91) | CA2CA1PPARACA12CA14 | |
| SCHEMBL10892940 | 0.77 | PPARA (0.91) | CA2CA1PPARACA12CA14 | |
| SCHEMBL3792249 | 0.77 | PPARA (0.91) | CA2CA1PPARACA12CA14 | |
| SCHEMBL5127346 | 0.76 | CA2 (0.64) | CA2CA1PPARACA12CA14 | |
| SCHEMBL3879124 | 0.75 | CA12 (0.34) | CA2CA1CA12CA14CA7 | |
| Acetic Acid SCHEMBL28034181 | 0.75 | CA2 (0.52) | CA2CA1PPARACA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057043-B2 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor | HOECHST SCHERING AGREVO GMBH (DE) | 2006-06-06 | — | — | US | disclosed |
| US-20050033047-A1 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-02-10 | — | — | US | disclosed |
| US-6790955-B2 | REACTING 2-SULFONAMIDO, NITROBENZOIC ACID COMPOUND WITH IN THE PRESENCE OF A HALOGENATING AGENT, WITH FORMATION OF THE CARBONYL HALIDE AND ITS REARRANGEMENT; AMMONOLYSIS AT SO2CL GROUP REDUCING AT THE NITRO GROUP; REACTING WITH CARBAMATE | HOECHST SCHERING AGREVO GMBH (DE) | 2004-09-14 | — | — | US | disclosed |
| US-20030096991-A1 | Processes for the preparation of aminophenylsulfonyl-ureas and intermediate products for the processes | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6500952-B1 | SUCH AS 5-AMINO-2-DIMETHYLAMINOCARBONYL-N-((4,6-DIMETHOXY-PYRIMIDIN-2-YL) -AMINOCARBONYL)BENZENESULFONAMIDE; HERBICIDES OR PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| US-4853025-A | HERBCIDES | E. I. DU PONT DE NEMOUR AND COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| US-4853025-A | HERBCIDES | E. I. DU PONT DE NEMOUR AND COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| US-4746355-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| US-4746355-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| US-4609395-A | Novel benzylsulfonylureas and arylsulfamoylureas N-[(substituted pyrimidin-2-yl)aminocarbonyl]-1-oxo-fused benzyl-7-methanesulfonamides useful as herbicides and plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4609395-A | Novel benzylsulfonylureas and arylsulfamoylureas N-[(substituted pyrimidin-2-yl)aminocarbonyl]-1-oxo-fused benzyl-7-methanesulfonamides useful as herbicides and plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033047-A1 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor | HNMT, PRMT3, CBR3 | CA2 616/4885CA1 121/4885PPARA 2825/4885 |
| US-20030096991-A1 | Processes for the preparation of aminophenylsulfonyl-ureas and intermediate products for the processes | HNMT, CPS1, HRH4 | CA2 1645/4885CA1 389/4885PPARA 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.