Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112926 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL7112755 | 0.81 | UBE2N (0.57) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL801935 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL16712195 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL6113216 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL742725 | 0.77 | KMT2A (0.49) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL1299062 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TSHRGAAKMT2ASMN1; SMN2 | |
| SCHEMBL246828 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL29642997 | 0.77 | KMT2A (0.49) | ALDH1A1TSHRGAAHTTKMT2A | |
| SCHEMBL1299059 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833723-B | The manufacture method of cyclic sulfonic acid ester and intermediate thereof | 和光纯药工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| EP-2757102-B1 | Intermediate for producing a cyclic sulfonic acid ester | WAKO PURE CHEM IND LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-8969591-B2 | Method for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| EP-2463281-B1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEM IND LTD (JP) | 2014-10-22 | — | — | EP | disclosed |
| EP-2757102-A1 | 1,3-propanesultone derivative useful in the preparation of a 1,3-propenesultone derivative | Wako Pure Chemical Industries, Ltd. (JP) | 2014-07-23 | — | — | EP | disclosed |
| CN-103833723-A | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEM IND LTD | 2014-06-04 | — | — | CN | disclosed |
| US-20140142324-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-05-22 | — | — | US | disclosed |
| US-8673963-B2 | Method for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| CN-102471305-B | Process for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEM IND LTD | 2014-01-29 | — | — | CN | disclosed |
| EP-2463281-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | Wako Pure Chemical Industries, Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20120130089-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142324-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | STS, TST, SULT1A1 | ALDH1A1 131/4885TSHR 1305/4885GAA 4276/4885 |
| US-20120130089-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | STS, TST, SULT1A1 | ALDH1A1 131/4885TSHR 1305/4885GAA 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.