Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25C | P30307 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553043 | 0.84 | TSHR (0.51) | TSHRCYP1A2CDC25BALDH1A1HSD17B10 | |
| SCHEMBL117199 | 0.84 | ILK (0.53) | TSHRALDH1A1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL260372 | 0.83 | ALDH1A1 (0.51) | TSHRCYP1A2CDC25BALDH1A1HSD17B10 | |
| Bromide SCHEMBL261347 | 0.82 | ALDH1A1 (0.50) | TSHRCYP1A2CDC25BALDH1A1HSD17B10 | |
| SCHEMBL20969720 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL11691158 | 0.77 | KMT2A (0.47) | CYP1A2ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL11689605 | 0.76 | ALDH1A1 (0.46) | CYP1A2ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL29351134 | 0.75 | NPC1 (0.52) | CYP1A2ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL28705957 | 0.75 | NPC1 (0.52) | CYP1A2ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL11690001 | 0.74 | SMN1; SMN2 (0.39) | TSHRALDH1A1HSD17B10KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159561-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2023-05-25 | — | — | US | disclosed |
| US-11578085-B2 | Heterocycle-substituted bicyclic azole pesticides | FMC CORPORATION (US) | 2023-02-14 | — | — | US | disclosed |
| EP-4105209-A2 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC Corporation (US) | 2022-12-21 | — | — | EP | disclosed |
| EP-3424919-B1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-112679467-A | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-107635984-B | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-112608300-A | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-06 | — | — | CN | disclosed |
| US-20210017192-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2021-01-21 | — | — | US | disclosed |
| US-10822351-B2 | Heterocycle-substituted bicyclic azole pesticides | FMC CORPORATION (US) | 2020-11-03 | — | — | US | disclosed |
| EP-3567036-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC Corporation (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-3424919-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC Corporation (US) | 2019-01-09 | — | — | EP | disclosed |
| US-10150782-B2 | Heterocycle-substituted bicyclic azole pesticides | FMC CORPORATION (US) | 2018-12-11 | — | — | US | disclosed |
| EP-3044220-B1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2018-11-07 | — | — | EP | disclosed |
| US-20180009827-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | E I du Ponte de Nemours and Company (US) | 2018-01-11 | — | — | US | disclosed |
| US-9802961-B2 | Heterocycle-substituted bicyclic azole pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170174707-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORPORATION | 2017-06-22 | — | — | US | disclosed |
| WO-2016144351-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | WO | disclosed |
| EP-3044220-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | E. I. du Pont de Nemours and Company (US) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015038503-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-03-19 | — | — | WO | disclosed |
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10822351-B2 | Heterocycle-substituted bicyclic azole pesticides | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
| US-20230159561-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | DDT, AADAC, AHR | TSHR 255/4885CYP1A2 10/4885CDC25B 1769/4885 |
| US-11578085-B2 | Heterocycle-substituted bicyclic azole pesticides | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
| US-20180009827-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
| US-10150782-B2 | Heterocycle-substituted bicyclic azole pesticides | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
| US-20210017192-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
| US-20170174707-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | TSHR 1382/4885CYP1A2 48/4885CDC25B 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.