Peldesine

Peldesine

SCHEMBL61136

Nc1nc(=O)c2[nH]cc(Cc3cccnc3)c2[nH]1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNP P00491 6/20 0.69
MPO P05164 1/20 0.42
PLA2G7 Q13093 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Peldesine SCHEMBL29364464 0.81 PNP (1.00) PNP
Peldesine SCHEMBL61135 0.81 PNP (1.00) PNP
Peldesine SCHEMBL6345442 0.74 PNP (0.82) PNP
SCHEMBL7714583 0.70 PLA2G7 (0.61) PNPPLA2G7
SCHEMBL7007907 0.69 PNP (0.55) PNPPLA2G7
SCHEMBL9281406 0.69 PNP (0.65) PNPPLA2G7
SCHEMBL9224582 0.69 PNP (0.70) PNPPLA2G7
SCHEMBL9231910 0.68 PNP (0.74) PNP
SCHEMBL6343588 0.66 PNP (1.00) PNP
SCHEMBL10728014 0.66 PNP (0.46) PNPMPOPLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8062 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2024-10-17 US claimed
US-11345956-B2 Methods and compositions related to prostate cancer therapeutics THE JOHNS HOPKINS UNIVERSITY (US) 2022-05-31 US claimed
US-11207289-B2 Use of benzofuran lignans to induce IL-25 expression and suppress mammary tumor metastasis ACADEMIA SINICA (TW) 2021-12-28 US claimed
US-20210060040-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2021-03-04 US claimed
EP-3191114-B1 OCCIDIOFUNGIN FORMULATIONS AND USES THEREOF UNIV MISSISSIPPI STATE (US) 2021-03-03 EP claimed
US-20200289454-A1 USE OF BENZOFURAN LIGNANS TO INDUCE IL-25 EXPRESSION AND SUPPRESS MAMMARY TUMOR METASTASIS Yang, Ning-Sun (TW) 2020-09-17 US claimed
US-20200270362-A1 MSLN TARGETING TRISPECIFIC PROTEINS AND METHODS OF USE HARPOON THERAPEUTICS, INC. 2020-08-27 US claimed
WO-2008039254-A2 RNA NANOPARTICLES AND NANOTUBES GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2008-04-03 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20040092583-A1 Treatment for inhibiting neoplastic lesions SHANAHAN-PRENDERGAST ELIZABETH (IE) 2004-05-13 US claimed
EP-1351678-A2 TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS Shanahan-Prendergast, Elizabeth (IE) 2003-10-15 EP claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
WO-2002053138-A2 TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS SHANAHAN-PRENDERGAST ELISABETH (IE) 2002-07-11 WO claimed
WO-2000040269-A2 PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF DISEASED TISSUES LEE CLARENCE C (US) 2000-07-13 WO claimed