Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106276 | 0.85 | PLA2G7 (0.36) | PLA2G7 | |
| SCHEMBL10655828 | 0.82 | TLR7 (0.39) | PLA2G7 | |
| SCHEMBL10728459 | 0.77 | MGMT (0.32) | — | |
| SCHEMBL7012765 | 0.77 | PLA2G7 (0.53) | PNPCYP19A1CYP11B1CYP11B2PLA2G7 | |
| SCHEMBL10656049 | 0.74 | L3MBTL1 (0.33) | — | |
| SCHEMBL10619999 | 0.72 | ALDH1A1 (0.49) | PNPPLA2G7HTTLMNA | |
| SCHEMBL7007907 | 0.68 | PNP (0.55) | PNPHRH4HRH3PLA2G7DAO | |
| SCHEMBL10865045 | 0.67 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2PLA2G7HTT | |
| SCHEMBL8541224 | 0.67 | CYP19A1 (0.53) | CYP19A1CYP11B1CYP11B2 | |
| Peldesine SCHEMBL61136 | 0.66 | PNP (0.69) | PNPPLA2G7MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710498-A | ANTIULCER AGENTS | IKEDA MOHANDO CO., LTD. (JP) | 1987-12-01 | — | — | US | disclosed |
| EP-0177016-A2 | Pyridyloxy derivatives | Ikeda Mohando Co., Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |