Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | PHGDH | O43175 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27884130 | 0.92 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2ALMNASIGMAR1 | |
| SCHEMBL2850013 | 0.87 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2ALMNASIGMAR1 | |
| SCHEMBL27791391 | 0.87 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2ALMNASIGMAR1 | |
| SCHEMBL10825084 | 0.87 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2ALMNASIGMAR1 | |
| SCHEMBL17275260 | 0.84 | MEN1 (0.69) | KMT2ASIGMAR1MEN1TSHRFAAH | |
| SCHEMBL17276624 | 0.84 | KDM4E (0.75) | ALDH1A1SMN1; SMN2LMNAKDM4EFAAH | |
| SCHEMBL30302091 | 0.84 | KDM4E (0.75) | ALDH1A1SMN1; SMN2LMNAKDM4EFAAH | |
| SCHEMBL5544496 | 0.84 | AKR1C3 (0.65) | ALDH1A1KMT2ASIGMAR1KDM4EMEN1 | |
| SCHEMBL16357989 | 0.84 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KMT2ALMNASIGMAR1 | |
| SCHEMBL771507 | 0.84 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KMT2ALMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059950-A | Compounds with proteasome agonistic activity, preparation method and application thereof | 浙大城市学院 | 2026-05-19 | — | — | CN | disclosed |
| US-8802675-B2 | Neuroprotective multifunctional compounds and pharmaceutical compositions comprising them | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (IL) | 2014-08-12 | — | — | US | disclosed |
| US-20120040993-A1 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2012-02-16 | — | — | US | disclosed |
| WO-2010086860-A2 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-08-05 | — | — | WO | disclosed |
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040993-A1 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | GSR, GRIN1, GRIN2A | ALDH1A1 1552/4885SMN1; SMN2 568/4885KMT2A 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.