Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | PHGDH | O43175 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299455 | 0.90 | SIGMAR1 (0.67) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL27791391 | 0.89 | ALDH1A1 (0.70) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL2850013 | 0.89 | ALDH1A1 (0.70) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL611401 | 0.87 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL16357989 | 0.85 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL3096649 | 0.85 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL7973808 | 0.85 | LMNA (0.67) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL1943497 | 0.85 | HRH3 (0.75) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL771507 | 0.85 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 | |
| SCHEMBL3222136 | 0.85 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61176578-A | — | — | None | — | — | JP | disclosed |
| JP-61280494-A | — | — | None | — | — | JP | disclosed |
| JP-S61280494-A | PRODUCTION OF PIPEMIDIC ACID | ROLLER JAPAN KK | 1986-12-11 | — | — | JP | disclosed |
| JP-S61176578-A | PIPERAZINE DERIVATIVE | ROLLER JAPAN KK | 1986-08-08 | — | — | JP | disclosed |