SCHEMBL611653

SCHEMBL611653

Cc1cc(Br)cc(I)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30016876 1.00
SCHEMBL156099 0.78
SCHEMBL1229565 0.78
SCHEMBL812374 0.78
SCHEMBL79108 0.78
SCHEMBL782213 0.78
SCHEMBL249769 0.78
SCHEMBL9397842 0.76 TTR (0.33)
SCHEMBL6291138 0.76 ALDH1A1 (0.48)
Fluoride SCHEMBL28049696 0.76 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS PROFUSA INC (US) 2026-02-26 US disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 EP disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 EP disclosed
US-12410160-B2 KHK inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2025-07-17 US disclosed
US-12285250-B2 Near-IR glucose sensors PROFUSA, INC (US) 2025-04-29 US disclosed
CN-119490498-A Cyanopyrimidine derivative organic compound, application thereof, perovskite solar cell and organic electroluminescent device 北京绿人科技有限责任公司 2025-02-21 CN disclosed
US-20240392186-A1 METAL COMPLEXES, MIXTURES, COMPOSITIONS AND ORGANIC ELECTRONIC DEVICES GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2024-11-28 US disclosed
EP-4421080-A1 METAL COMPLEX, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC COMPONENT Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2024-08-28 EP disclosed
US-20100266714-A1 P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN MERCK SHARP & DOHME LLC 2010-10-21 US disclosed
US-20100093865-A1 SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ACUCELA, INC. (US) 2010-04-15 US disclosed
WO-2010028088-A2 SULFUR-LINKED COMPOUNDS FOR TREATING OPTHALMIC DISEASES AND DISORDERS ACUCELA, INC. (US) 2010-03-11 WO disclosed
US-20090281149-A1 Amine Derivative Compounds for Treating Ophthalmic Diseases and Disorders ACUCELA, INC. (US) 2009-11-12 US disclosed
WO-2009130434-A1 INHIBITORS OF IKK-β SERINE-THREONINE PROTEIN KINASE CHROMA THERAPEUTICS LTD. (GB) 2009-10-29 WO disclosed
WO-2009130434-A1 INHIBITORS OF IKK-β SERINE-THREONINE PROTEIN KINASE CHROMA THERAPEUTICS LTD. (GB) 2009-10-29 WO disclosed
EP-2111223-A1 AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS Acucela, Inc. (US) 2009-10-28 EP disclosed
WO-2009058216-A1 AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ACUCELA, INC. (US) 2009-05-07 WO disclosed
WO-2009058216-A1 AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS ACUCELA, INC. (US) 2009-05-07 WO disclosed
WO-2008016522-A2 HIV REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2008-02-07 WO disclosed