Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119825 | 0.91 | CYP2C9 (0.49) | CYP2C9CYP3A4CYP2C19KCNH2KIF11 | |
| SCHEMBL2295568 | 0.89 | CYP2C9 (0.48) | CYP2C9CYP3A4CYP2C19KCNH2ANO1 | |
| SCHEMBL2296799 | 0.87 | CYP2C9 (0.43) | CYP2C9CYP3A4CYP2C19KCNH2ANO1 | |
| SCHEMBL6119722 | 0.85 | CYP2C9 (0.45) | CYP2C9CYP3A4CYP2C19KCNH2ANO1 | |
| SCHEMBL2302690 | 0.84 | CYP2C9 (0.45) | CYP2C9CYP3A4CYP2C19KCNH2ANO1 | |
| SCHEMBL6120266 | 0.83 | CYP2C9 (0.41) | TRPV1CYP2C9CYP3A4CYP2C19KCNH2 | |
| SCHEMBL2298467 | 0.81 | CYP2C9 (0.47) | CYP2C9CYP3A4CYP2C19KCNH2ANO1 | |
| SCHEMBL6120327 | 0.80 | CYP2C9 (0.46) | CYP2C9CYP3A4CYP2C19KCNH2ANO1 | |
| SCHEMBL2298808 | 0.80 | CYP2C9 (0.59) | CYP2C9CYP3A4CYP2C19KCNH2 | |
| SCHEMBL2298218 | 0.80 | CYP2C9 (0.48) | CYP2C9CYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |