Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27258792 | 0.86 | HTR3A (0.44) | HTR3ARAB9AL3MBTL1KMT2ATLR7 | |
| SCHEMBL2759552 | 0.82 | HRH4 (0.49) | HTR3ARAB9AL3MBTL1KMT2ATLR7 | |
| SCHEMBL4647849 | 0.81 | ALDH1A1 (0.55) | KMT2ATDP1SMN1; SMN2AOC3 | |
| SCHEMBL12675278 | 0.81 | HTR3A (0.47) | HTR3ARAB9AL3MBTL1KMT2ATLR7 | |
| SCHEMBL19003513 | 0.81 | HTR3A (0.47) | HTR3ARAB9AL3MBTL1KMT2ATLR7 | |
| SCHEMBL2322917 | 0.81 | ALDH1A1 (0.57) | HTR3ARAB9AL3MBTL1KMT2ATDP1 | |
| SCHEMBL5122324 | 0.81 | HTR3A (0.47) | HTR3ARAB9AL3MBTL1KMT2ATLR7 | |
| SCHEMBL11988947 | 0.81 | SMO (0.52) | HTR3ARAB9AL3MBTL1KMT2AHRH4 | |
| SCHEMBL6118949 | 0.81 | HRH3 (0.45) | — | |
| SCHEMBL8281445 | 0.79 | HRH4 (0.46) | HTR3ARAB9AL3MBTL1KMT2ATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068210-A1 | PYRIDYL-THIAZOLYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | WO | disclosed |