Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121195 | 0.92 | BRAF (0.32) | JAK2BRAFWDR5 | |
| SCHEMBL6120580 | 0.91 | SLC34A1 (0.32) | JAK2BRAF | |
| SCHEMBL6121002 | 0.90 | BRAF (0.34) | JAK2BRAFWDR5 | |
| SCHEMBL6120670 | 0.84 | PTGES2 (0.37) | BRAFWDR5 | |
| SCHEMBL6120692 | 0.84 | TP53 (0.37) | BRAF | |
| SCHEMBL6120617 | 0.83 | BRAF (0.32) | BRAFWDR5 | |
| SCHEMBL6120439 | 0.83 | PTGES2 (0.35) | JAK2BRAF | |
| SCHEMBL6120657 | 0.82 | PTGES2 (0.37) | JAK2BRAF | |
| SCHEMBL6121823 | 0.82 | CYP3A4 (0.36) | JAK2BRAFWDR5 | |
| SCHEMBL6121578 | 0.82 | BRAF (0.33) | JAK2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |