Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 14/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120439 | 0.93 | PTGES2 (0.35) | PTGES2JAK2BRAFBTKEGFR | |
| SCHEMBL6120967 | 0.91 | WDR5 (0.36) | PTGES2JAK2BRAF | |
| SCHEMBL6121578 | 0.91 | BRAF (0.33) | PTGES2JAK2BRAFBTKEGFR | |
| SCHEMBL6121300 | 0.90 | PTGES2 (0.38) | PTGES2BRAFBTKEGFR | |
| SCHEMBL6120754 | 0.87 | BTK (0.33) | BRAFBTKEGFRCSNK1E | |
| SCHEMBL6121002 | 0.86 | BRAF (0.34) | PTGES2JAK2BRAF | |
| SCHEMBL6121837 | 0.86 | PTGES2 (0.32) | PTGES2JAK2 | |
| SCHEMBL6121078 | 0.85 | PTGES2 (0.35) | PTGES2BRAF | |
| SCHEMBL6120796 | 0.85 | CSNK1D (0.39) | BTKEGFRCSNK1E | |
| SCHEMBL6121823 | 0.84 | CYP3A4 (0.36) | PTGES2JAK2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |