SCHEMBL612249

SCHEMBL612249

O=C(c1ccc(O)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.62
ALDH1A1 P00352 4/20 0.55
TP53 P04637 1/20 0.55
SRD5A2 P31213 2/20 0.53
MAPT P10636 5/20 0.50
LMNA P02545 3/20 0.50
HTT P42858 2/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 1/20 0.48
LIG1 P18858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7466437 0.90 ALDH1A1 (0.61) MAPK1ALDH1A1TP53SRD5A2MAPT
SCHEMBL610783 0.85 SRD5A2 (0.72) MAPK1ALDH1A1TP53SRD5A2MAPT
SCHEMBL610759 0.84 ALDH1A1 (0.53) ALDH1A1TP53SRD5A2MAPTLMNA
SCHEMBL5022620 0.84 ALDH1A1 (0.53) MAPK1ALDH1A1TP53SRD5A2MAPT
SCHEMBL4342906 0.84 MAPT (0.53) ALDH1A1TP53SRD5A2MAPTLMNA
SCHEMBL809876 0.84 ALDH1A1 (0.53) MAPK1ALDH1A1TP53SRD5A2MAPT
SCHEMBL13538924 0.84 ALDH1A1 (0.53) MAPK1ALDH1A1TP53SRD5A2MAPT
SCHEMBL13252856 0.84 ALDH1A1 (0.53) ALDH1A1TP53SRD5A2MAPTLMNA
SCHEMBL13309942 0.84 CNR2 (0.60) ALDH1A1TP53SRD5A2MAPTLMNA
SCHEMBL13309938 0.84 CNR2 (0.60) ALDH1A1TP53SRD5A2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2206547-B1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND PROCESSES FOR THE PRODUCTION OF THE SAME, POLYMERS AND PROTON CONDUCTIVE MEMBRANES OF THESE COMPOUNDS JSR CORP (JP) 2016-03-16 EP disclosed
EP-1906473-B1 ELECTRODE PASTE FOR USE IN SOLID POLYMER FUEL CELL JSR CORP (JP) 2014-02-12 EP disclosed
US-8399148-B2 Varnish for a solid polymer fuel cell JSR CORPORATION (JP) 2013-03-19 US disclosed
EP-1947717-B1 ELECTRODE CATALYST LAYER JSR CORP (JP) 2013-02-13 EP disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8236206-B2 Electrode catalyst layer JSR CORPORATION (JP) 2012-08-07 US disclosed
US-20120040271-A1 ELECTRODE ELECTROLYTE FOR SOLID POLYMER-TYPE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2012-02-16 US disclosed
EP-1845122-B1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR CORP (JP) 2011-11-16 EP disclosed
EP-1845122-B1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR CORP (JP) 2011-11-16 EP disclosed
US-8043762-B2 Polyphenylene-containing electrode paste JSR CORPORATION (JP) 2011-10-25 US disclosed
EP-0646143-B1 MACROMONOMERS HAVING REACTIVE SIDE GROUPS MAXDEM INC (US) 2000-10-18 EP disclosed
US-5869592-A Macromonomers having reactive side groups MAXDEM INCORPORATED (US) 1999-02-09 US disclosed
US-5830945-A HIGH STRENGTH; STIFFNESS MAXDEM, INCORPORATED (US) 1998-11-03 US disclosed
US-5625010-A Macromonomers having reactive side groups MAXDEM INCORPORATED (US) 1997-04-29 US disclosed
EP-0646143-A4 MACROMONOMERS HAVING REACTIVE SIDE GROUPS. MAXDEM INC (US) 1996-07-24 EP disclosed
US-5539048-A Macromonomers having reactive side groups MAXDEM INCORPORATED (US) 1996-07-23 US disclosed
US-5512630-A Macromonomers having reactive side groups MAXDEM INCORPORATED (US) 1996-04-30 US disclosed
US-5496893-A Macromonomers having reactive side groups MAXDEM INCORPORATED (US) 1996-03-05 US disclosed
EP-0646143-A1 MACROMONOMERS HAVING REACTIVE SIDE GROUPS MAXDEM INCORPORATED (US) 1995-04-05 EP disclosed
WO-1993004098-A1 MACROMONOMERS HAVING REACTIVE SIDE GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed