SCHEMBL809876

SCHEMBL809876

O=C(c1ccc(S)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TP53 P04637 2/20 0.53
SRD5A2 P31213 4/20 0.51
MAPT P10636 2/20 0.47
RAB9A P51151 1/20 0.47
LMNA P02545 2/20 0.46
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
RECQL P46063 1/20 0.44
NR4A1 P22736 1/20 0.43
CNR2 P34972 1/20 0.42
IDO1 P14902 1/20 0.41
MAPK1 P28482 1/20 0.41
MITF O75030 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TLR9 Q9NR96 1/20 0.41
JAK2 O60674 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7466437 0.89 ALDH1A1 (0.61) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL612249 0.84 MAPK1 (0.62) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL14403864 0.82 SRD5A2 (0.42) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL13538924 0.82 ALDH1A1 (0.53) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL610759 0.82 ALDH1A1 (0.53) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL13309938 0.82 CNR2 (0.60) ALDH1A1TP53SRD5A2MAPTLMNA
SCHEMBL13309942 0.82 CNR2 (0.60) ALDH1A1TP53SRD5A2MAPTLMNA
SCHEMBL5022620 0.82 ALDH1A1 (0.53) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL13252856 0.82 ALDH1A1 (0.53) ALDH1A1TP53SRD5A2MAPTRAB9A
SCHEMBL4342906 0.82 MAPT (0.53) ALDH1A1TP53SRD5A2MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9409861-B2 Mercapto benzophenone compounds, compositions and preparation method thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2016-08-09 US claimed
US-20150246878-A1 MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF Insight High Technology (Beijing) Co. Ltd. (CN) 2015-09-03 US claimed
EP-2738159-A1 MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF Insight High Technology Co., Ltd. (CN) 2014-06-04 EP claimed
US-20130150479-A1 Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2013-06-13 US claimed
EP-2738159-B1 MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF INSIGHT HIGH TECH BEIJING CO LTD (CN) 2018-04-18 EP disclosed
US-9409861-B2 Mercapto benzophenone compounds, compositions and preparation method thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2016-08-09 US disclosed
US-20150246878-A1 MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF Insight High Technology (Beijing) Co. Ltd. (CN) 2015-09-03 US disclosed
US-9061979-B2 Mercapto benzophenone compounds, compositions and preparations method thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2015-06-23 US disclosed
EP-2738159-A1 MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF Insight High Technology Co., Ltd. (CN) 2014-06-04 EP disclosed
US-20130150479-A1 Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof Insight High Technology (Beijing) Co. Ltd. (CN) 2013-06-13 US disclosed
EP-1693405-B1 PROTON CONDUCTING MEMBRANE AND PROCESS FOR PRODUCING THE SAME JSR CORP (JP) 2012-05-02 EP disclosed
EP-1845122-B1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR CORP (JP) 2011-11-16 EP disclosed
US-7893303-B2 Polyarylene, process for producing the same, solid polyelectrolyte, and proton-conductive film JSR CORPORATION (JP) 2011-02-22 US disclosed
EP-1619739-B1 Membrane-electrode structure for solid polymer fuel cell and solid polymer fuel cell HONDA MOTOR CO LTD (JP) 2010-09-22 EP disclosed
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film JSR CORPORATION (JP) 2008-01-17 US disclosed
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film JSR CORPORATION (JP) 2008-01-17 US disclosed
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film JSR CORPORATION (JP) 2008-01-17 US disclosed
EP-1845122-A1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR Corporation (JP) 2007-10-17 EP disclosed
EP-1845122-A1 POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM JSR Corporation (JP) 2007-10-17 EP disclosed
US-20060188768-A1 Membrane-electrode assembly for use in solid polymer electrolyte fuel cell and solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2006-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246878-A1 MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF MIF, TST, BMI1 ALDH1A1 73/4885TP53 3943/4885SRD5A2 1071/4885
US-20130150479-A1 Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof MIF, TST, BMI1 ALDH1A1 73/4885TP53 3943/4885SRD5A2 1071/4885
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film PARG, PUF60, PARN ALDH1A1 3441/4885TP53 4505/4885SRD5A2 3716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.