⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL29133218 | 0.85 | DAO (0.43) | — | |
| SCHEMBL18869535 | 0.73 | ALAD (0.52) | — | |
| SCHEMBL4244577 | 0.71 | DAO (0.44) | — | |
| SCHEMBL40746 | 0.71 | — | — | |
| SCHEMBL19357535 | 0.67 | — | — | |
| SCHEMBL5004859 | 0.67 | — | — | |
| SCHEMBL771882 | 0.67 | CES2 (0.43) | — | |
| SCHEMBL422305 | 0.67 | — | — | |
| SCHEMBL2016588 | 0.67 | CES2 (0.43) | — | |
| SCHEMBL2679589 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554009-A | Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide | 南京工业大学 | 2023-08-08 | — | — | CN | claimed |
| CN-110117270-B | Preparation method of 3- (thiophene-2-yl) cyclohexanone framework compound | 山西大学 | 2021-07-27 | — | — | CN | claimed |
| US-20150291623-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2015-10-15 | — | — | US | claimed |
| US-20120295897-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2012-11-22 | — | — | US | claimed |
| CN-102256983-A | Spirooxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2011-11-23 | — | — | CN | claimed |
| EP-2350090-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2011-08-03 | — | — | EP | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| US-20040014764-A1 | N-myristoyltransferase inhibitor compositions and methods of use | SMITH CHARLES D (US) | 2004-01-22 | — | — | US | claimed |
| CN-122070275-A | Heterocyclic compound and application thereof | 成都麻沸散医药科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122010938-A | Pyrido [1, 2-a ] pyrimidine mesoionic derivative containing five-membered heterocyclic structure, and preparation and application thereof | 贵州大学 | 2026-05-12 | — | — | CN | disclosed |
| EP-4725493-A2 | POLYCYCLIC COMPOUNDS FOR INHIBITING RNA HELICASE DHX33 AND USE THEREOF | Shenzhen Keye Life Technologies, Co., Ltd. (CN) | 2026-04-15 | — | — | EP | disclosed |
| US-20260034101-A1 | ANTIMITOTIC AMIDES FOR THE TREATMENT OF CANCER AND PROLIFERATIVE DISORDERS | FROST BIOLOGIC INC (US) | 2026-02-05 | — | — | US | disclosed |
| EP-3889133-B1 | 4-[[2-[[5-[1-(1H-INDOL-2-YL)-2-(PHENYL)-1-ETHEN-1-YL]-2-PYRIDINYL]OXY]ETHYL]AMINO]-2-BUTENAMIDE DERIVATIVES FOR THE TREATMENT OF ESTROGEN RECEPTOR POSITIVE BREAST CANCER | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2026-01-28 | — | — | EP | disclosed |
| EP-0196001-B1 | THIOPHENE RING-SUBSTITUTED ALPHA-(ALKYLAMINOPROPIONYL)-THIOPHENE DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-01-25 | — | — | EP | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0196001-A1 | Thiophene ring-substituted alpha-(alkylaminopropionyl)-thiophene derivatives, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1986-10-01 | — | — | EP | disclosed |
| US-4535092-A | Acylanilides having antiandrogenic activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-08-13 | — | — | US | disclosed |
| EP-0079191-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-05-18 | — | — | EP | disclosed |