Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.48 |
| ▸ | MGLL | Q99685 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LOXL4 | Q96JB6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816142 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ALDH2MGLLTP53MAPT | |
| Thiram SCHEMBL9314198 | 0.72 | ALDH1A1 (0.54) | ALDH1A1ALDH2MGLLTP53MAPT | |
| Thiram SCHEMBL20473181 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ALDH2MGLLTP53MAPT | |
| Thiram SCHEMBL20473180 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ALDH2MGLLTP53MAPT | |
| Thiram SCHEMBL22471732 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ALDH2MGLLTP53MAPT | |
| SCHEMBL6254604 | 0.70 | EPHX1 (0.35) | MGLLTP53MAPTHSD17B10GMNN | |
| Thiram SCHEMBL9246528 | 0.69 | ALDH1A1 (0.50) | ALDH1A1ALDH2MGLLTP53MAPT | |
| SCHEMBL283865 | 0.68 | ALDH1A1 (0.86) | ALDH1A1ALDH2MGLLTP53MAPT | |
| SCHEMBL14166676 | 0.67 | CES2 (0.46) | ALDH1A1HSD17B10ALOX15KMT2ATSHR | |
| SCHEMBL11292896 | 0.67 | CES2 (0.42) | ALDH1A1TP53MAPTHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428866-B1 | LUBRICATING OIL COMPOSITION | NIPPON OIL CORP (JP) | 2012-05-23 | — | — | EP | disclosed |