Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484120 | 0.78 | ALDH1A1 (0.66) | ALDH1A1POLBTDP1GAAMEN1 | |
| SCHEMBL1874186 | 0.77 | ALDH1A1 (0.68) | ALDH1A1POLBTDP1MEN1LMNA | |
| SCHEMBL17009272 | 0.73 | CYP19A1 (0.49) | ALDH1A1POLBEDNRBEDNRAGAA | |
| SCHEMBL6121906 | 0.72 | CYP2D6 (0.68) | ALDH1A1POLBTDP1GAANSD2 | |
| SCHEMBL6958157 | 0.72 | PTGS2 (0.46) | ALDH1A1TDP1EDNRBEDNRAHSD17B10 | |
| SCHEMBL3100642 | 0.70 | BCAT2 (0.50) | EDNRBEDNRAKMT2A | |
| SCHEMBL14372090 | 0.70 | NSD2 (0.73) | ALDH1A1POLBTDP1GAANSD2 | |
| SCHEMBL5350394 | 0.69 | ALDH1A1 (0.73) | ALDH1A1POLBTDP1GAAHSD17B10 | |
| SCHEMBL5298689 | 0.69 | KMT2A (0.59) | ALDH1A1POLBTDP1GAANSD2 | |
| SCHEMBL7418333 | 0.69 | BCAT2 (0.49) | ALDH1A1EDNRBEDNRAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640721-A2 | AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS | Texas Heart Institute (US) | 2013-09-25 | — | — | EP | claimed |
| WO-2012068251-A2 | AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS | TEXAS HEART INSTITUTE (US) | 2012-05-24 | — | — | WO | claimed |