Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855633 | 0.83 | ACHE (0.34) | — | |
| SCHEMBL6126300 | 0.71 | — | — | |
| SCHEMBL856224 | 0.67 | ACHE (0.37) | — | |
| SCHEMBL855662 | 0.64 | PDK1 (0.36) | — | |
| SCHEMBL857638 | 0.63 | CACNA1G (0.32) | — | |
| SCHEMBL857386 | 0.61 | PDK1 (0.33) | — | |
| SCHEMBL858000 | 0.60 | PDK1 (0.32) | — | |
| SCHEMBL14638271 | 0.57 | TNKS2 (0.58) | — | |
| SCHEMBL856254 | 0.55 | PDK1 (0.32) | — | |
| SCHEMBL3598581 | 0.55 | KMT2A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640366-A2 | BENZOXAZEPINES AS INHIBITORS OF PI3K/MTOR AND METHODS OF THEIR USE AND MANUFACTURE | Exelixis, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068096-A2 | BENZOXAZEPINES AS INHIBITORS OF PI3K/MTOR AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2012-05-24 | — | — | WO | disclosed |