Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223753 | 0.91 | DPP4 (0.53) | L3MBTL1DPP4HPGDTSHRKMT2A | |
| SCHEMBL25231697 | 0.91 | DPP4 (0.53) | L3MBTL1DPP4HPGDTSHRKMT2A | |
| SCHEMBL25237209 | 0.91 | DPP4 (0.53) | L3MBTL1DPP4HPGDTSHRKMT2A | |
| SCHEMBL27603657 | 0.81 | HPGD (0.64) | L3MBTL1DPP4HPGDTSHRALDH1A1 | |
| SCHEMBL11021735 | 0.81 | HPGD (0.64) | L3MBTL1DPP4HPGDTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5412784 | 0.80 | HPGD (0.62) | L3MBTL1DPP4HPGDTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6872103 | 0.80 | HPGD (0.62) | L3MBTL1DPP4HPGDTSHRALDH1A1 | |
| SCHEMBL2730960 | 0.78 | L3MBTL1 (0.52) | L3MBTL1DPP4HPGDTSHRKMT2A | |
| SCHEMBL6202280 | 0.78 | L3MBTL1 (0.51) | L3MBTL1HPGDTSHRKMT2AMEN1 | |
| SCHEMBL6128481 | 0.77 | L3MBTL1 (0.48) | L3MBTL1DPP4HPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058128-A2 | CAPROLACTAM MGLUR5 RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |