Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618774 | 0.95 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| SCHEMBL3245199 | 0.95 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| SCHEMBL3245339 | 0.95 | L3MBTL1 (0.54) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| SCHEMBL12527918 | 0.94 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| Hydrochloric Acid SCHEMBL12494265 | 0.94 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| Hydrochloric Acid SCHEMBL12494266 | 0.94 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| SCHEMBL7933318 | 0.90 | ALDH1A1 (0.47) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| SCHEMBL4224772 | 0.90 | ALDH1A1 (0.47) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| SCHEMBL4224776 | 0.90 | ALDH1A1 (0.47) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 | |
| Hydrochloric Acid SCHEMBL6818480 | 0.89 | ALDH1A1 (0.46) | L3MBTL1KMT2AMEN1ALDH1A1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |