SCHEMBL6129181

SCHEMBL6129181

CCOC(=O)CCC1CN1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
USP2 O75604 1/20 0.44
CYP1A2 P05177 1/20 0.44
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
TRPA1 O75762 1/20 0.40
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
SMYD3 Q9H7B4 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27801248 0.86 ALDH1A1 (0.38) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL8537018 0.83 DGKA (0.38) TDP1MAPT
SCHEMBL24739562 0.83 ALDH1A1 (0.38) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL24739475 0.81 ALDH1A1 (0.38) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL24740407 0.81 ALDH1A1 (0.38) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL24739210 0.81 ALDH1A1 (0.38) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL2044063 0.80 TDP1 (0.42) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL19958799 0.80 TDP1 (0.42) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL24740457 0.80 TDP1 (0.42) ALDH1A1ALOX15TDP1USP2CYP1A2
SCHEMBL1070810 0.80 THRB (0.32) ALDH1A1ALOX15TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6974874-B2 Reduction of monomer content and stabilization of polyaziridines BAYER MATERIALSCIENCE LLC (US) 2005-12-13 US disclosed
US-6927297-B2 Reduction of monomer content and stabilization of polyaziridines BAYER MATERIALSCIENCE LLC (US) 2005-08-09 US disclosed
US-20040087762-A1 Reduction of monomer content and stabilization of polyaziridines COVESTRO LLC 2004-05-06 US disclosed
US-20040087763-A1 Reduction of monomer content and stabilization of polyaziridines COVESTRO LLC 2004-05-06 US disclosed
US-6667407-B2 Forming isocyanate scavengers with reduced monomer content; reacting acrylate and aziridine components BAYER POLYMERS LLC 2003-12-23 US disclosed
US-4788108-A PHOTOPOLYMERIZATION PPG INDUSTRIES, INC. (US) 1988-11-29 US disclosed
EP-0158874-A2 Curable iminated resins from aminoplasts and hydroxylcontaining carboxylic acids PPG INDUSTRIES, INC. (US) 1985-10-23 EP disclosed
US-4535128-A LOW TEMPERATURE CURING, STORAGE STABILITY NIPPON PAINT CO., LTD. (JP) 1985-08-13 US disclosed
US-4293457-A POLYESTER; AMINOPLAST CURING AGENT; THERMOPLASTIC ACRYLIC POLYMER; CELLULOSE ACETATE BUTYRATE, EPOXY RESIN, OR VINYL ESTER-VINYL HALIDE COPOLYMER PPG INDUSTRIES, INC. (US) 1981-10-06 US disclosed
US-4232090-A Sealerless primers PPG INDUSTRIES, INC. (US) 1980-11-04 US disclosed
US-4187258-A AMINOPLAST CURING AGENT; POLYESTER, POLYETHER, OR POLYURETHANE, THERMOPLASTIC ACRYLIC RESIN PPG INDUSTRIES, INC. (US) 1980-02-05 US disclosed
US-4018849-A Polyurethane polyol compositions modified with an alkylenimine PPG INDUSTRIES, INC. (US) 1977-04-19 US disclosed
US-3966667-A Preparation of non-aqueous thermosetting acrylic polymer dispersions PPG INDUSTRIES, INC. (US) 1976-06-29 US disclosed
US-3953391-A ALKYLENEIMINE-MODIFIED ACRYLIC COPOLYMERSACID PPG INDUSTRIES, INC. (US) 1976-04-27 US disclosed