Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 14/20 | 0.43 |
| ▸ | PLG | P00747 | 14/20 | 0.43 |
| ▸ | F10 | P00742 | 8/20 | 0.43 |
| ▸ | F2 | P00734 | 7/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 7/20 | 0.43 |
| ▸ | HPN | P05981 | 3/20 | 0.38 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556596 | 0.88 | PLAU (0.41) | PLAUPLGF10F2ST14 | |
| SCHEMBL4557815 | 0.84 | ITGB3 (0.42) | PLAUPLGF10F2ST14 | |
| SCHEMBL4459041 | 0.84 | ITGB3 (0.36) | PLAUPLGF10F2ST14 | |
| SCHEMBL4557910 | 0.84 | PLAU (0.33) | PLAUPLGF10F2ST14 | |
| SCHEMBL6129266 | 0.77 | PLAU (0.61) | PLAUPLGF10F2ST14 | |
| Hydrochloric Acid SCHEMBL6550006 | 0.72 | PLAU (0.35) | PLAUPLGF10F2ST14 | |
| SCHEMBL3747259 | 0.71 | F10 (0.58) | PLAUPLGF10F2ST14 | |
| SCHEMBL4462974 | 0.71 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL6551292 | 0.68 | MGLL (0.30) | — | |
| SCHEMBL2953288 | 0.68 | PLAU (0.48) | PLAUPLGF10F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511721-B1 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | WILEX AG (DE) | 2009-07-01 | — | — | EP | disclosed |