Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.83 |
| ▸ | PPARA | Q07869 | 13/20 | 0.83 |
| ▸ | PPARG | P37231 | 6/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510515 | 0.94 | PPARD (0.79) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| Gw501516 SCHEMBL68714 | 0.91 | PPARD (1.00) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| Gw501516 SCHEMBL29356729 | 0.91 | PPARD (1.00) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL5519969 | 0.90 | PPARD (0.98) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6712219 | 0.90 | PPARD (0.85) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4810184 | 0.90 | PPARD (0.67) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL6632955 | 0.88 | PPARD (0.65) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4890171 | 0.86 | PPARD (0.64) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL3814837 | 0.86 | PPARD (0.78) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL4674209 | 0.86 | PPARD (0.75) | PPARDPPARAPPARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101542-A1 | Combination therapy for controlling appetites | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-05-12 | — | — | US | disclosed |
| US-20050054730-A1 | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-03-10 | — | — | US | disclosed |
| WO-2005002524-A2 | COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES OF OLEOYLETHANOLAMIDE-LIKE COMPOUNDS AND MODULATORS OF PPARα | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101542-A1 | Combination therapy for controlling appetites | FAAH, FAAH2, GPR119 | PPARD 26/4885PPARA 7/4885PPARG 16/4885 |
| US-20050054730-A1 | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha | PPARA, CNR2, CNR1 | PPARD 9/4885PPARA 1/4885PPARG 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.