Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787560 | 1.00 | MAPT (0.72) | MAPTRAB9AKMT2ACYP1A2KDM4E | |
| SCHEMBL30990554 | 0.86 | RAB9A (0.81) | MAPTRAB9AKMT2ACYP1A2KDM4E | |
| SCHEMBL29240838 | 0.86 | RAB9A (0.81) | MAPTRAB9AKMT2ACYP1A2KDM4E | |
| SCHEMBL318311 | 0.84 | MAPT (1.00) | MAPTRAB9ACYP1A2KDM4ENPC1 | |
| SCHEMBL318312 | 0.84 | MAPT (1.00) | MAPTRAB9ACYP1A2KDM4ENPC1 | |
| SCHEMBL23743203 | 0.83 | CYP1A1 (0.57) | MAPTRAB9AKMT2ACYP1A2KDM4E | |
| SCHEMBL19076268 | 0.81 | RELA (0.55) | MAPTRAB9AKMT2ACYP1A2NPC1 | |
| SCHEMBL1178920 | 0.81 | RAB9A (0.69) | MAPTRAB9AKMT2ACYP1A2KDM4E | |
| SCHEMBL1178923 | 0.81 | RAB9A (0.69) | MAPTRAB9AKMT2ACYP1A2KDM4E | |
| SCHEMBL19076159 | 0.80 | MAPT (0.62) | MAPTRAB9AKMT2ACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10300155-B2 | Alpha-synuclein ligands | WASHINGTON UNIVERSITY (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | WASHINGTON UNIVERSITY (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | WASHINGTON UNIVERSITY (US) | 2017-07-06 | — | — | US | disclosed |
| US-20150008425-A1 | SUBSTRATE FOR ORGANIC ELECTRONIC DEVICE | LG CHEM, LTD. (KR) | 2015-01-08 | — | — | US | disclosed |
| US-20150001525-A1 | SUBSTRATE FOR ORGANIC ELECTRONIC DEVICE | LG DISPLAY CO., LTD. (KR) | 2015-01-01 | — | — | US | disclosed |
| US-20050195318-A1 | Organic information reading unit and information reading device using the same | PANASONIC CORPORATION (JP) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10300155-B2 | Alpha-synuclein ligands | SNCA, PARK7, LRRK2 | MAPT 58/4885RAB9A 152/4885KMT2A 4633/4885 |
| US-20170189566-A1 | ALPHA-SYNUCLEIN LIGANDS | SNCA, PARK7, LRRK2 | MAPT 58/4885RAB9A 152/4885KMT2A 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.