⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435763 | 0.83 | KMT2A (0.37) | — | |
| SCHEMBL4929498 | 0.80 | HTT (0.39) | — | |
| SCHEMBL9435754 | 0.79 | HTT (0.35) | — | |
| SCHEMBL2880798 | 0.77 | ALOX5 (0.39) | — | |
| SCHEMBL11552954 | 0.77 | SLC6A2 (0.36) | — | |
| SCHEMBL20213737 | 0.77 | KMT2A (0.38) | — | |
| SCHEMBL12311962 | 0.76 | — | — | |
| SCHEMBL94688 | 0.76 | — | — | |
| SCHEMBL827372 | 0.75 | ALOX5 (0.35) | — | |
| SCHEMBL5711552 | 0.75 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050084512-A1 | Tridimensional biocompatible support structure for bioartificial organs and uses thereof | TRANSFERT PLUS, SOCIETE EN COMMANDITE (CA) | 2005-04-21 | — | — | US | disclosed |
| EP-1387885-A1 | TRIDIMENSIONAL BIOCOMPATIBLE SUPPORT STRUCTURE FOR BIOARTIFICIAL ORGANS AND USES THEREOF | UNIVERSITE DU QUEBEC A MONTREAL (CA) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002088331-A1 | TRIDIMENSIONAL BIOCOMPATIBLE SUPPORT STRUCTURE FOR BIOARTIFICIAL ORGANS AND USES THEREOF | UNIVERSITE DU QUEBEC A MONTREAL (CA) | 2002-11-07 | — | — | WO | disclosed |
| EP-0874828-A4 | COMPOSITION FOR TREATING PAIN | LILLY CO ELI (US) | 1999-09-01 | — | — | EP | disclosed |
| CN-1040979-C | Antipsychotic method | NOVO NORDISK AS (DK) | 1998-12-02 | — | — | CN | disclosed |
| EP-0874828-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997020819-A1 | COMPOSITION FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1997-06-12 | — | — | WO | disclosed |
| WO-1997017962-A1 | METHOD FOR TREATING ANXIETY | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |
| US-5527813-A | THERAPEUTICALLY ACTIVE AZABICYCLIC COMPOUNDS USEFUL AS STIMULANTS OF THE COGNITIVE FUNCTION OF THE FOREBRAIN AND IN THE TREATMENT OF ALZHEIMER'S DISEASE | NOVO NORDISK A/S (DK) | 1996-06-18 | — | — | US | disclosed |
| US-5338571-A | Surface modification of substrates to provide covalent bonding with fullerenes | NORTHWESTERN UNIVERSITY (US) | 1994-08-16 | — | — | US | disclosed |