Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.61 |
| ▸ | NMT2 | O60551 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 6/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2508780 | 1.00 | NOD1 (0.61) | NOD1NMT2NMT1TLR2HRH1 | |
| SCHEMBL29527293 | 0.93 | NOD1 (0.58) | NOD1NMT2NMT1FURINSLC6A5 | |
| SCHEMBL1573989 | 0.93 | NOD1 (0.58) | NOD1NMT2NMT1FURINSLC6A5 | |
| SCHEMBL30985184 | 0.91 | NOD1 (0.60) | NOD1NMT2NMT1SLC6A5FOLH1 | |
| SCHEMBL2508754 | 0.89 | NOD1 (0.46) | NOD1NMT2NMT1FURINGHSR | |
| SCHEMBL2508755 | 0.89 | NOD1 (0.46) | NOD1NMT2NMT1FURINGHSR | |
| SCHEMBL19529151 | 0.88 | NOD1 (0.68) | NOD1NMT2NMT1TLR2ROCK2 | |
| SCHEMBL20529374 | 0.88 | NMT2 (0.43) | NOD1NMT2NMT1FURINFOLH1 | |
| SCHEMBL2512125 | 0.87 | FOLH1 (0.53) | NOD1NMT2NMT1FURINFOLH1 | |
| SCHEMBL29794236 | 0.87 | FOLH1 (0.53) | NOD1NMT2NMT1FURINFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107976-A4 | ANTI-ENDOTOXIC, ANTIMICROBIAL CATIONIC PEPTIDES AND METHODS OF USE THEREFOR | UNIV BRITISH COLUMBIA (CA) | 2005-01-05 | — | — | EP | disclosed |
| EP-1107976-A1 | ANTI-ENDOTOXIC, ANTIMICROBIAL CATIONIC PEPTIDES AND METHODS OF USE THEREFOR | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012528-A1 | ANTI-ENDOTOXIC, ANTIMICROBIAL CATIONIC PEPTIDES AND METHODS OF USE THEREFOR | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2000-03-09 | — | — | WO | disclosed |