SCHEMBL1573989

SCHEMBL1573989

C[C@H](N)C(=O)N[C@H](CCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](C)C(=O)N[C@H](C)C(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 8/20 0.58
▸ FOLH1 Q04609 2/20 0.47
▸ NMT2 O60551 1/20 0.47
▸ NMT1 P30419 1/20 0.47
▸ SLC6A5 Q9Y345 1/20 0.46
▸ SLC15A2 Q16348 1/20 0.41
▸ CPB2 Q96IY4 2/20 0.40
▸ FURIN P09958 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29527293 1.00 NOD1 (0.58) NOD1FOLH1NMT2NMT1SLC6A5
SCHEMBL30985184 0.98 NOD1 (0.60) NOD1FOLH1NMT2NMT1SLC6A5
SCHEMBL6129561 0.93 NOD1 (0.61) NOD1FOLH1NMT2NMT1SLC6A5
SCHEMBL2508780 0.93 NOD1 (0.61) NOD1FOLH1NMT2NMT1SLC6A5
SCHEMBL20529374 0.90 NMT2 (0.43) NOD1FOLH1NMT2NMT1CPB2
SCHEMBL21330513 0.90 NOD1 (0.68) NOD1FOLH1NMT2NMT1SLC6A5
SCHEMBL2512125 0.89 FOLH1 (0.53) NOD1FOLH1NMT2NMT1CPB2
SCHEMBL30512604 0.89 FOLH1 (0.53) NOD1FOLH1NMT2NMT1CPB2
SCHEMBL29451703 0.89 FOLH1 (0.60) NOD1FOLH1NMT2NMT1SLC6A5
SCHEMBL29451463 0.89 FOLH1 (0.60) NOD1FOLH1NMT2NMT1SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206261-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING CLAVULANIC ACID OR DERIVATIVE THEREOF FOR THE TREATMENT OF BEHAVIORAL DISEASES REVAAX PHARMACEUTICALS LLC (US) 2006-03-08 — — EP claimed
EP-1212055-A4 NEUROTHERAPEUTIC COMPOSITION AND METHOD REVAAX PHARMACEUTICALS LLC (US) 2005-09-07 — — EP claimed
US-6627625-B1 Beta-lactam antibiotics and beta -lactamase inhibitors provides significant neurotropic effects in warm-blooded vertebrates evidenced inter by anxiolytic and antiaggressive behavior modification ans enhanced cognition REVAAX PHARMACEUTICALS, LLC 2003-09-30 — — US claimed
JP-2003506490-A — — 2003-02-18 — — JP claimed
EP-1212055-A1 NEUROTHERAPEUTIC COMPOSITION AND METHOD Revaax Pharmaceuticals LLC (US) 2002-06-12 — — EP claimed
WO-2001012184-A1 NEUROTHERAPEUTIC COMPOSITION AND METHOD REVAAX PHARMACEUTICALS, LLC (US) 2001-02-22 — — WO claimed
US-20250037787-A1 CONCENTRATION BOUNDS IN LARGE NETWORKS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-01-30 — — US disclosed
US-20150094229-A1 METHODS FOR THE SCREENING OF ANTIBACTERIAL SUBSTANCES UNIVERSITE RENE DESCARTES (FR) 2015-04-02 — — US disclosed
EP-1212055-B1 Neurotherapeutic composition comprising a beta-lactam compound REVAAX PHARMACEUTICALS LLC (US) 2011-08-03 — — EP disclosed
EP-2305251-A2 Pharmaceutical compositions comprising clavulanic acid or derivative thereof for the treatment of sexual disorder Revaax Pharmaceuticals LLC (US) 2011-04-06 — — EP disclosed
US-7842683-B2 Neurotherapeutic compositions and method REVAAX PHARMACEUTICALS, LLC (US) 2010-11-30 — — US disclosed
US-20100249090-A1 NEUROTHERAPEUTIC COMPOSITION AND METHOD THEREFOR KOPPEL GARY A 2010-09-30 — — US disclosed
US-20090311714-A1 Methods for the Screening of Antibacterial Substances UNIVERSITE RENE DESCARTES (FR) 2009-12-17 — — US disclosed
CN-1382047-A Compositions and methods for treating neuropathy REVAAX PHARMACEUTICALS LLC (US) 2002-11-27 — — CN disclosed
WO-2002064087-A2 NEUROTHERAPEUTIC USE OF CARBOXYPEPTIDASE INHIBITORS REVAAX PHARMACEUTICALS, LLC (US) 2002-08-22 — — WO disclosed
EP-1212055-A1 NEUROTHERAPEUTIC COMPOSITION AND METHOD Revaax Pharmaceuticals LLC (US) 2002-06-12 — — EP disclosed
EP-1206261-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CLAVULANIC ACID OR DERIVATIVE THEREOF FOR THE TREATMENT OF BEHAVIORAL DISEASES Revaax Pharmaceuticals LLC (US) 2002-05-22 — — EP disclosed
US-20020028761-A1 Neurotherapeutic use of carboxypeptidase inhibitors REVAAX PHARMACEUTICALS, LLC 2002-03-07 — — US disclosed
WO-2001012171-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CLAVULANIC ACID OR DERIVATIVE THEREOF FOR THE TREATMENT OF BEHAVIORAL DISEASES REVAAX PHARMACEUTICALS, LLC (US) 2001-02-22 — — WO disclosed
WO-2001012184-A1 NEUROTHERAPEUTIC COMPOSITION AND METHOD REVAAX PHARMACEUTICALS, LLC (US) 2001-02-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028761-A1 Neurotherapeutic use of carboxypeptidase inhibitors THOP1, DPEP1, PREP NOD1 1895/4885FOLH1 8/4885NMT2 626/4885
US-20100249090-A1 NEUROTHERAPEUTIC COMPOSITION AND METHOD THEREFOR PREP, ANPEP, MME NOD1 3321/4885FOLH1 19/4885NMT2 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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