Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.50 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | ASPH | Q12797 | 2/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28665454 | 0.94 | KDM4E (0.56) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| Water SCHEMBL336347 | 0.94 | KDM4E (0.56) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| SCHEMBL7767700 | 0.94 | KDM4E (0.56) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| SCHEMBL70035 | 0.91 | KDM4E (0.59) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| Water SCHEMBL6129699 | 0.89 | KDM4E (0.52) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| Hydrochloric Acid SCHEMBL11594387 | 0.88 | KDM4E (0.56) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| Iodide SCHEMBL7459681 | 0.86 | KDM4E (0.54) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| SCHEMBL17712841 | 0.81 | SIRT6 (0.64) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| SCHEMBL17725120 | 0.79 | KDM4E (0.48) | KDM4EHCAR2NAPRTP4HTMP4HA1 | |
| SCHEMBL241781 | 0.79 | KDM4E (0.48) | KDM4EHCAR2NAPRTP4HTMP4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105776-A4 | LIGHT-POLARIZING PARTICLES OF IMPROVED PARTICLE SIZE DISTRIBUTION | RESEARCH FRONTIERS INC (US) | 2005-04-13 | — | — | EP | disclosed |
| US-6334967-B1 | REACTING PRECURSOR OF POLYHALIDE WITH IODINE, HYDROHALIDE ACID OR AMMONIUM, ALKALI OR ALKALINE EARTH METAL HALIDE | RSEARCH FRONTIERS INCORPORATED | 2002-01-01 | — | — | US | disclosed |
| EP-1105776-A1 | LIGHT-POLARIZING PARTICLES OF IMPROVED PARTICLE SIZE DISTRIBUTION | RESEARCH FRONTIERS INCORPORATED (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000003177-A1 | LIGHT-POLARIZING PARTICLES OF IMPROVED PARTICLE SIZE DISTRIBUTION | RESEARCH FRONTIERS INCORPORATED (US) | 2000-01-20 | — | — | WO | disclosed |