SCHEMBL6130143

SCHEMBL6130143

Cc1cc2c(C)c(O)c(C)cc2c(C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.52
LDHB P07195 3/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
PKM P14618 1/20 0.39
ADORA3 P0DMS8 3/20 0.39
ADORA2A P29274 2/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13021187 0.84 LDHA (0.45) LDHALDHBCA1CA2LMNA
SCHEMBL19012177 0.83 LDHA (0.41) LDHALDHBCA1CA2LMNA
SCHEMBL68382 0.80 CA1 (0.56) CA1CA2LMNAHTTMAPT
SCHEMBL21985718 0.78 LMNA (0.47) LDHALDHBLMNAHTTMAPT
SCHEMBL9810544 0.78 CA1 (0.42) LDHALDHBCA1CA2LMNA
SCHEMBL21985687 0.77 ESR1 (0.42) LDHALDHBLMNAHTTALDH1A1
SCHEMBL22507728 0.77 LDHA (0.45) LDHALDHBLMNAHTTALDH1A1
SCHEMBL21133304 0.77 LMNA (0.50) LDHALDHBCA1CA2LMNA
SCHEMBL19012171 0.75 LDHA (0.41) LDHALDHBCA1CA2LMNA
SCHEMBL29729030 0.75 CA1 (0.50) CA1CA2LMNAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317497-A4 POLYESTER RESINS WITH IMPROVED PROPERTIES POLYMERS AUSTRALIA PTY LTD (AU) 2005-03-02 EP claimed
US-20040116619-A1 Polyester resins with improved properties POLYMERS AUSTRALIA PTY LIMITED (AU) 2004-06-17 US claimed
EP-1317497-A1 POLYESTER RESINS WITH IMPROVED PROPERTIES Polymers Australia PTY Limited (AU) 2003-06-11 EP claimed
WO-2002022705-A1 POLYESTER RESINS WITH IMPROVED PROPERTIES POLYMERS AUSTRALIA PTY LTD (AU) 2002-03-21 WO claimed
US-20040116619-A1 Polyester resins with improved properties POLYMERS AUSTRALIA PTY LIMITED (AU) 2004-06-17 US disclosed