SCHEMBL13021187

SCHEMBL13021187

Cc1cc2cc(C)c(O)c(C)c2cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.45
LDHB P07195 2/20 0.45
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
KDM4E B2RXH2 5/20 0.34
MAPT P10636 5/20 0.34
GAA P10253 3/20 0.34
ALDH1A1 P00352 3/20 0.34
PKM P14618 1/20 0.34
NPC1 O15118 1/20 0.34
MITF O75030 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
AGTR1 P30556 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130143 0.84 LDHA (0.52) LDHALDHBCA1CA2CYP1A2
SCHEMBL19400459 0.81 CYP3A4 (0.37) LDHALDHBCA1CA2CYP1A2
SCHEMBL13021182 0.80 LDHA (0.41) LDHALDHBCA1CA2CYP1A2
SCHEMBL15835617 0.78 ESR1 (0.55) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL21985694 0.78 CYP1A2 (0.46) CYP1A2LMNAHTTALDH1A1PKM
SCHEMBL3953630 0.75 LMNA (0.52) CYP1A2LMNAHTTMAPTGAA
SCHEMBL30071634 0.75 LMNA (0.52) CYP1A2LMNAHTTMAPTGAA
SCHEMBL6130175 0.74 CA1 (0.46) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL22507728 0.73 LDHA (0.45) LDHALDHBCYP1A2LMNAHTT
SCHEMBL21985687 0.73 ESR1 (0.42) LDHALDHBCYP1A2CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8308998-B2 Polarizing film, coating liquid, and image display NITTO DENKO CORPORATION (JP) 2012-11-13 US disclosed
US-20100288166-A1 POLARIZING FILM, COATING LIQUID, AND IMAGE DISPLAY NITTO DENKO CORPORATION (JP) 2010-11-18 US disclosed