Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15648404 | 0.82 | TNNC1 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL16327651 | 0.79 | MBOAT4 (0.52) | MBOAT4NPC1RAB9ASMN1; SMN2AAK1 | |
| SCHEMBL16327642 | 0.79 | MBOAT4 (0.52) | MBOAT4NPC1RAB9ASMN1; SMN2AAK1 | |
| Bromide SCHEMBL15648033 | 0.78 | ASAH1 (0.40) | HTR2APLK1CYSLTR2CYSLTR1 | |
| SCHEMBL6130110 | 0.78 | TNNC1 (0.46) | MBOAT4PLK1PLK3MEN1KMT2A | |
| SCHEMBL7620622 | 0.77 | CETP (0.39) | MBOAT4NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL20176308 | 0.76 | AAK1 (0.60) | NPC1RAB9ASMN1; SMN2LMNAAAK1 | |
| SCHEMBL23944942 | 0.76 | MBOAT4 (0.56) | MBOAT4NPC1RAB9ASMN1; SMN2AAK1 | |
| SCHEMBL6528663 | 0.76 | RARB (0.46) | MBOAT4MEN1KMT2A | |
| SCHEMBL6130100 | 0.75 | CETP (0.39) | MBOAT4AAK1PLK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315735-A4 | PHOSPHATE DERIVATIVES AS IMMUNOREGULATORY AGENTS | MERCK & CO INC (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-1315735-A1 | PHOSPHATE DERIVATIVES AS IMMUNOREGULATORY AGENTS | Merck & Co., Inc. (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002018395-A1 | PHOSPHATE DERIVATIVES AS IMMUNOREGULATORY AGENTS | MERCK & CO., INC. (US) | 2002-03-07 | — | — | WO | disclosed |