Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | HTR6 | P50406 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5849269 | 0.99 | HTR1A (0.68) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9760084 | 0.92 | HTR1A (0.61) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9760311 | 0.89 | HTR1A (0.58) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9759010 | 0.85 | HTR1A (0.64) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9760092 | 0.84 | HTR1A (0.62) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9760094 | 0.83 | DRD2 (0.67) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL8332830 | 0.83 | HTR1A (0.66) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9769531 | 0.82 | HTR1A (0.60) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL6618184 | 0.82 | DRD2 (0.66) | HTR1AADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL9760272 | 0.79 | DRD2 (0.67) | HTR1AADRA1AADRA1DADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3090027-A | — | — | None | — | — | JP | disclosed |
| EP-1334723-A4 | SUSTAINED-RELEASE PREPARATION CONTAINING 5-ACETYL-4,6-DIMETHYL-2- 2- 4-(2-METHOXYPHENYL)PIPERAZINYL]ETHYLAMINO]PYRIMIDINE TRIHYDROCHLORIDE AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2005-08-31 | — | — | EP | disclosed |
| EP-1334723-A4 | SUSTAINED-RELEASE PREPARATION CONTAINING 5-ACETYL-4,6-DIMETHYL-2- 2- 4-(2-METHOXYPHENYL)PIPERAZINYL]ETHYLAMINO]PYRIMIDINE TRIHYDROCHLORIDE AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2005-08-31 | — | — | EP | disclosed |
| EP-1334723-A1 | SUSTAINED-RELEASE PREPARATION CONTAINING 5-ACETYL-4,6-DIMETHYL-2- 2- 4-(2-METHOXYPHENYL)PIPERAZINYL]ETHYLAMINO]PYRIMIDINE TRIHYDROCHLORIDE AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002034268-A1 | SUSTAINED-RELEASE PREPARATION CONTAINING 5-ACETYL-4,6-DIMETHYL-2-[2-[4-(2-METHOXYPHENYL)PIPERAZINYL]ETHYLAMINO]PYRIMIDINE TRIHYDROCHLORIDE AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-05-02 | — | — | WO | disclosed |
| WO-2002034268-A1 | SUSTAINED-RELEASE PREPARATION CONTAINING 5-ACETYL-4,6-DIMETHYL-2-[2-[4-(2-METHOXYPHENYL)PIPERAZINYL]ETHYLAMINO]PYRIMIDINE TRIHYDROCHLORIDE AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-05-02 | — | — | WO | disclosed |
| US-5075308-A | Method for treating urinary obstruction | HITACHI CHEMICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| JP-H0390027-A | DYSURIA REMEDY | HITACHI CHEM CO LTD | 1991-04-16 | — | — | JP | disclosed |