Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.66 |
| ▸ | DRD2 | P14416 | 6/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.66 |
| ▸ | HTR7 | P34969 | 3/20 | 0.66 |
| ▸ | HTR6 | P50406 | 3/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760177 | 0.93 | HTR1A (0.73) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9759010 | 0.86 | HTR1A (0.64) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9760272 | 0.84 | DRD2 (0.67) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9769531 | 0.84 | HTR1A (0.60) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6130213 | 0.83 | HTR1A (0.69) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9760084 | 0.83 | HTR1A (0.61) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL5849269 | 0.82 | HTR1A (0.68) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9759666 | 0.81 | HTR1A (0.60) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9760311 | 0.80 | HTR1A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL6934502 | 0.80 | DRD2 (0.66) | HTR1ADRD2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11092458-A | — | — | None | — | — | JP | disclosed |
| JP-H1192458-A | NEW PYRIMIDINE DERIVATIVE | ONO PHARMACEUT CO LTD | 1999-04-06 | — | — | JP | disclosed |
| US-5075308-A | Method for treating urinary obstruction | HITACHI CHEMICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |