Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585911 | 0.86 | SLC9A1 (0.60) | HTR2AHTR2CHTR2BSLC9A1TSHR | |
| SCHEMBL15938770 | 0.85 | HTR2A (0.50) | HTR2AHTR2CHTR2BSLC9A1TSHR | |
| SCHEMBL1586594 | 0.81 | ALDH1A1 (0.41) | HTR2AHTR2CHTR2BSLC9A1TSHR | |
| SCHEMBL6130264 | 0.81 | ALDH1A1 (0.41) | HTR2AHTR2CHTR2BSLC9A1TSHR | |
| SCHEMBL1586035 | 0.77 | DPP4 (0.54) | HTR2AHTR2CHTR2BSLC9A1TSHR | |
| SCHEMBL1586523 | 0.74 | MEN1 (0.52) | TSHRALDH1A1CYP2C9KDM4EMEN1 | |
| SCHEMBL13882534 | 0.74 | DPP4 (0.42) | HTR2AHTR2CHTR2BSLC9A1TSHR | |
| SCHEMBL3421675 | 0.72 | FFAR1 (0.45) | SLC9A1ALDH1A1KDM4EHPGD | |
| SCHEMBL20342920 | 0.72 | SLC9A1 (0.43) | SLC9A1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3422742 | 0.70 | SLC9A1 (0.62) | HTR2AHTR2CHTR2BSLC9A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347952-A4 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1347952-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002046142-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2002-06-13 | — | — | WO | disclosed |